MedChem Express

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MedChemExpress has an experienced team of custom synthesis chemists, led by an impressive group of Ph.D.'s. With this team, we have the capability of supporting all kinds of chemistry projects of multiple step syntheses of complex labeled molecules, including metabolites and steroids. Following scientific and technological innovation, challenging traditional thinking, MedChemExpress has always been committed to develop quality products that exceed international standards on cost and reliability, to create the most advanced synthetic route. With high experiences in preparing a large numbers of different biologically active molecules, we provide rapid synthesis of new products. That is why we can consistently deliver your custom synthesis compounds faster than any other company.

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β-Lapachone 10mM/1mL  | ≥98%

MedChem Express

β-Lapachone is a naturally occurring O-naphthoquinone, acts as a topoisomerase I inhibitor, and induces apoptosis by inhibiting cell cycle progression. IC50 & Target: Topoisomerase I[1] In Vitro: β-Lapachone is a topoisomerase I inhibitor. β-Lapachone (25 μM) inhibits camptothecin-induced DNA cleavage[1]. β-Lapachone (10-40 μM) significantly reduces the colony-forming ability of CHO cells, and is cytotoxic in […]

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β-Lapachone 10mg  | ≥98%

MedChem Express

β-Lapachone is a naturally occurring O-naphthoquinone, acts as a topoisomerase I inhibitor, and induces apoptosis by inhibiting cell cycle progression. IC50 & Target: Topoisomerase I[1] In Vitro: β-Lapachone is a topoisomerase I inhibitor. β-Lapachone (25 μM) inhibits camptothecin-induced DNA cleavage[1]. β-Lapachone (10-40 μM) significantly reduces the colony-forming ability of CHO cells, and is cytotoxic in […]

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β-Lapachone 50mg  | ≥98%

MedChem Express

β-Lapachone is a naturally occurring O-naphthoquinone, acts as a topoisomerase I inhibitor, and induces apoptosis by inhibiting cell cycle progression. IC50 & Target: Topoisomerase I[1] In Vitro: β-Lapachone is a topoisomerase I inhibitor. β-Lapachone (25 μM) inhibits camptothecin-induced DNA cleavage[1]. β-Lapachone (10-40 μM) significantly reduces the colony-forming ability of CHO cells, and is cytotoxic in […]

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β-Lapachone 100mg  | ≥98%

MedChem Express

β-Lapachone is a naturally occurring O-naphthoquinone, acts as a topoisomerase I inhibitor, and induces apoptosis by inhibiting cell cycle progression. IC50 & Target: Topoisomerase I[1] In Vitro: β-Lapachone is a topoisomerase I inhibitor. β-Lapachone (25 μM) inhibits camptothecin-induced DNA cleavage[1]. β-Lapachone (10-40 μM) significantly reduces the colony-forming ability of CHO cells, and is cytotoxic in […]

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β-Melanocyte Stimulating Hormone (MSH), human 1mg  | ≥98%

MedChem Express

β-Melanocyte Stimulating Hormone (MSH), human is a melanocortin (MC) receptor agonist. IC50 & Target: Melanocortin[1] In Vitro: β-Melanocyte Stimulating Hormone is a powerful anti-inflammatory agent which effect is brought by activation of the central MC3/MC4 receptors and thereby inhibits NO production by inhibiting the translocation of transcription factor NF-κB to the nuclei of the brain […]

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β-Melanocyte Stimulating Hormone (MSH), human 5mg  | ≥98%

MedChem Express

β-Melanocyte Stimulating Hormone (MSH), human is a melanocortin (MC) receptor agonist. IC50 & Target: Melanocortin[1] In Vitro: β-Melanocyte Stimulating Hormone is a powerful anti-inflammatory agent which effect is brought by activation of the central MC3/MC4 receptors and thereby inhibits NO production by inhibiting the translocation of transcription factor NF-κB to the nuclei of the brain […]

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β-Melanocyte Stimulating Hormone (MSH), human 10mg  | ≥98%

MedChem Express

β-Melanocyte Stimulating Hormone (MSH), human is a melanocortin (MC) receptor agonist. IC50 & Target: Melanocortin[1] In Vitro: β-Melanocyte Stimulating Hormone is a powerful anti-inflammatory agent which effect is brought by activation of the central MC3/MC4 receptors and thereby inhibits NO production by inhibiting the translocation of transcription factor NF-κB to the nuclei of the brain […]

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β-Nicotinamide mononucleotide 10mg  | ≥98%

MedChem Express

β-Nicotinamide mononucleotide is a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.

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β-Nicotinamide mononucleotide 50mg  | ≥98%

MedChem Express

β-Nicotinamide mononucleotide is a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.

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β-Nicotinamide mononucleotide 100mg  | ≥98%

MedChem Express

β-Nicotinamide mononucleotide is a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.

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β-Nicotinamide mononucleotide 10mM/1mL  | ≥98%

MedChem Express

β-Nicotinamide mononucleotide is a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.

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β3-AR agonist 2 5mg  | ≥98%

MedChem Express

β3-AR agonist 2 is a potent and selective β3-adrenergic receptor (β3-AR) agonist with an EC50 of 8 nM. IC50 & Target: EC50: 8 nM (β3-adrenergic receptor)[1] In Vitro: β3-AR agonist 2 (Compound 26e) is found to be potent and selective at the β3 receptor, nearly completely abolishes intrinsic activity at either the β1 or β2 […]

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β3-AR agonist 2 10mg  | ≥98%

MedChem Express

β3-AR agonist 2 is a potent and selective β3-adrenergic receptor (β3-AR) agonist with an EC50 of 8 nM. IC50 & Target: EC50: 8 nM (β3-adrenergic receptor)[1] In Vitro: β3-AR agonist 2 (Compound 26e) is found to be potent and selective at the β3 receptor, nearly completely abolishes intrinsic activity at either the β1 or β2 […]

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β3-AR agonist 2 1mg  | ≥98%

MedChem Express

β3-AR agonist 2 is a potent and selective β3-adrenergic receptor (β3-AR) agonist with an EC50 of 8 nM. IC50 & Target: EC50: 8 nM (β3-adrenergic receptor)[1] In Vitro: β3-AR agonist 2 (Compound 26e) is found to be potent and selective at the β3 receptor, nearly completely abolishes intrinsic activity at either the β1 or β2 […]

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γ-1-Melanocyte Stimulating Hormone (MSH), amide 5mg  | ≥98%

MedChem Express

γ-1-Melanocyte Stimulating Hormone (MSH), amide is a 11-amino acid peptide. γ-1-Melanocyte Stimulating Hormone (MSH) regulates sodium (Na+) balance and blood pressure through activation of the melanocortin receptor 3 (MC3-R). IC50 & Target: Melanocortin receptor 3 (MC3-R)[1] In Vitro: γ-Melanocyte Stimulating Hormone (γ-MSH) regulates a multitude of metabolic functions including energy homeostasis, food intake, sodium (Na+) […]

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γ-1-Melanocyte Stimulating Hormone (MSH), amide 10mg  | ≥98%

MedChem Express

γ-1-Melanocyte Stimulating Hormone (MSH), amide is a 11-amino acid peptide. γ-1-Melanocyte Stimulating Hormone (MSH) regulates sodium (Na+) balance and blood pressure through activation of the melanocortin receptor 3 (MC3-R). IC50 & Target: Melanocortin receptor 3 (MC3-R)[1] In Vitro: γ-Melanocyte Stimulating Hormone (γ-MSH) regulates a multitude of metabolic functions including energy homeostasis, food intake, sodium (Na+) […]

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γ-1-Melanocyte Stimulating Hormone (MSH), amide 1mg  | ≥98%

MedChem Express

γ-1-Melanocyte Stimulating Hormone (MSH), amide is a 11-amino acid peptide. γ-1-Melanocyte Stimulating Hormone (MSH) regulates sodium (Na+) balance and blood pressure through activation of the melanocortin receptor 3 (MC3-R). IC50 & Target: Melanocortin receptor 3 (MC3-R)[1] In Vitro: γ-Melanocyte Stimulating Hormone (γ-MSH) regulates a multitude of metabolic functions including energy homeostasis, food intake, sodium (Na+) […]

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γ-Aminobutyric acid 100mg  | ≥98%

MedChem Express

γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2]. IC50 & Target: GABA Receptor[1][2]

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γ-Aminobutyric acid 10mM/1mL  | ≥98%

MedChem Express

γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2]. IC50 & Target: GABA Receptor[1][2]

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γ-Glu-Phe 50mg  | ≥98%

MedChem Express

γ-Glu-Phe is a γ-3 glutamyl dipeptide found in sourdough. In Vitro: γ-Glu-Phe, γ-Glu-Met and γ-Glu-Val, are identified in sourdough by liquid chromatography-tandem mass spectrometry in MRM mode. γ-Glutamyl dipeptides are found in higher concentrations in sourdough fermented with L. reuteri when compared to the chemically acidified controls. Proteolysis is an important factor for generation of […]

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γ-Glu-Phe 5mg  | ≥98%

MedChem Express

γ-Glu-Phe is a γ-3 glutamyl dipeptide found in sourdough. In Vitro: γ-Glu-Phe, γ-Glu-Met and γ-Glu-Val, are identified in sourdough by liquid chromatography-tandem mass spectrometry in MRM mode. γ-Glutamyl dipeptides are found in higher concentrations in sourdough fermented with L. reuteri when compared to the chemically acidified controls. Proteolysis is an important factor for generation of […]

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γ-Glu-Phe 10mg  | ≥98%

MedChem Express

γ-Glu-Phe is a γ-3 glutamyl dipeptide found in sourdough. In Vitro: γ-Glu-Phe, γ-Glu-Met and γ-Glu-Val, are identified in sourdough by liquid chromatography-tandem mass spectrometry in MRM mode. γ-Glutamyl dipeptides are found in higher concentrations in sourdough fermented with L. reuteri when compared to the chemically acidified controls. Proteolysis is an important factor for generation of […]

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γ-Glu-Phe 100mg  | ≥98%

MedChem Express

γ-Glu-Phe is a γ-3 glutamyl dipeptide found in sourdough. In Vitro: γ-Glu-Phe, γ-Glu-Met and γ-Glu-Val, are identified in sourdough by liquid chromatography-tandem mass spectrometry in MRM mode. γ-Glutamyl dipeptides are found in higher concentrations in sourdough fermented with L. reuteri when compared to the chemically acidified controls. Proteolysis is an important factor for generation of […]

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γ-Oryzanol 1g  | ≥98%

MedChem Express

γ-Oryzanol is a potent DNA methyltransferases (DNMTs) inhibitor in the striatum of mice. γ-Oryzanol significantly inhibits the activities of DNMT1 (IC50=3.2 μM), DNMT3a (IC50=22.3 μM). IC50 & Target: IC50: 3.2 μM (DNMT1), 22.3 μM (DNMT3a)[1] In Vitro: γ-Oryzanol significantly inhibits the activities of DNMT1 (IC50=3.2 μM), DNMT 3a (IC50=22.3 μM) and DNMT 3b (maximum inhibition […]

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γ-Oryzanol 10mM/1mL  | ≥98%

MedChem Express

γ-Oryzanol is a potent DNA methyltransferases (DNMTs) inhibitor in the striatum of mice. γ-Oryzanol significantly inhibits the activities of DNMT1 (IC50=3.2 μM), DNMT3a (IC50=22.3 μM). IC50 & Target: IC50: 3.2 μM (DNMT1), 22.3 μM (DNMT3a)[1] In Vitro: γ-Oryzanol significantly inhibits the activities of DNMT1 (IC50=3.2 μM), DNMT 3a (IC50=22.3 μM) and DNMT 3b (maximum inhibition […]

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δ-Sleep Inducing Peptide 25mg  | ≥98%

MedChem Express

δ-Sleep Inducing Peptide is a neuropeptide, with antioxidant and anxiolytic properties. In Vivo: In rabbit infused with δ-Sleep Inducing Peptide (DSIP), the spindle activity is increased, and heart and respiration rate are moderately decreased. δ-Sleep Inducing Peptide (DSIP) may act as a programming modulator at supra-operational level rather than as a transmitter at operational level[1]. […]

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δ-Sleep Inducing Peptide 5mg  | ≥98%

MedChem Express

δ-Sleep Inducing Peptide is a neuropeptide, with antioxidant and anxiolytic properties. In Vivo: In rabbit infused with δ-Sleep Inducing Peptide (DSIP), the spindle activity is increased, and heart and respiration rate are moderately decreased. δ-Sleep Inducing Peptide (DSIP) may act as a programming modulator at supra-operational level rather than as a transmitter at operational level[1]. […]

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δ-Sleep Inducing Peptide 10mg  | ≥98%

MedChem Express

δ-Sleep Inducing Peptide is a neuropeptide, with antioxidant and anxiolytic properties. In Vivo: In rabbit infused with δ-Sleep Inducing Peptide (DSIP), the spindle activity is increased, and heart and respiration rate are moderately decreased. δ-Sleep Inducing Peptide (DSIP) may act as a programming modulator at supra-operational level rather than as a transmitter at operational level[1]. […]

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