MedChem Express

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MedChemExpress has an experienced team of custom synthesis chemists, led by an impressive group of Ph.D.'s. With this team, we have the capability of supporting all kinds of chemistry projects of multiple step syntheses of complex labeled molecules, including metabolites and steroids. Following scientific and technological innovation, challenging traditional thinking, MedChemExpress has always been committed to develop quality products that exceed international standards on cost and reliability, to create the most advanced synthetic route. With high experiences in preparing a large numbers of different biologically active molecules, we provide rapid synthesis of new products. That is why we can consistently deliver your custom synthesis compounds faster than any other company.

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LP23 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

LP23 is a non-arylmethylamine PD-1/PD-L1 inhibitor (IC50: 16.7 nM) with anti-tumor activity. LP23 restores immune cell function in HepG2/Jurkat T cells and promotes HepG2 cell death. LP23 is active in vivo in the B16-F10 tumor model (TGI=88.6% at 30 mg/kg)[1].

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LPd peroxida probe | MedChemExpress (MCE) 50 μg  | ≥98.00%

MedChem Express

LPd peroxida probe, a marker of ferroptosis, is a useful fluorescent probe for investigating the roles of lipid peroxidation in a variety of cell pathophysiologies. LPd peroxida probe reduces lipid hydroperoxides to lipid alcohols and is used for imaging lipid hydroperoxides in living cells[1][2][3].

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LRP1 Antibody | MedChemExpress (MCE) 10 uL  | ≥98.00%

MedChem Express

LRP1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 505 kDa, targeting to LRP1. It can be used for WB,IHC-F,IHC-P,ICC/IF,IP assays with tag free, in the background of Human, Mouse, Rat.

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LRP1 Antibody | MedChemExpress (MCE) 50 uL  | ≥98.00%

MedChem Express

LRP1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 505 kDa, targeting to LRP1. It can be used for WB,IHC-F,IHC-P,ICC/IF,IP assays with tag free, in the background of Human, Mouse, Rat.

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LRP1 Antibody | MedChemExpress (MCE) 100 uL  | ≥98.00%

MedChem Express

LRP1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 505 kDa, targeting to LRP1. It can be used for WB,IHC-F,IHC-P,ICC/IF,IP assays with tag free, in the background of Human, Mouse, Rat.

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LRP6 Antibody | MedChemExpress (MCE) 10 uL  | ≥98.00%

MedChem Express

LRP6 Antibody is a non-conjugated and Mouse origined monoclonal antibody about 180 kDa, targeting to LRP6. It can be used for WB,IHC-P assays with tag free, in the background of Human.

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LRP6 Antibody | MedChemExpress (MCE) 50 uL  | ≥98.00%

MedChem Express

LRP6 Antibody is a non-conjugated and Mouse origined monoclonal antibody about 180 kDa, targeting to LRP6. It can be used for WB,IHC-P assays with tag free, in the background of Human.

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LRP6 Antibody | MedChemExpress (MCE) 100 uL  | ≥98.00%

MedChem Express

LRP6 Antibody is a non-conjugated and Mouse origined monoclonal antibody about 180 kDa, targeting to LRP6. It can be used for WB,IHC-P assays with tag free, in the background of Human.

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LRRK2-IN-10 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

LRRK2-IN-10 (compound 34) is a potent, mutation-selective, and brain penetrant G2019S-LRRK2 kinase inhibitor with IC50s of 11 nM and 5.2 nM for G2019S-LRRK2 pS935 and G2019S-LRRK2 pS1292, respectively. LRRK2-IN-10 has the potential for Parkinson’s disease research[1].

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LRRK2/NUAK1/TYK2-IN-1 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

LRRK2/NUAK1/TYK2-IN-1 (conpound 226) shows inhibitory activity toward LRRK2 (Wt), LRRK2 (G2019), TYK2 and NUAK1, with IC50 values lower than 10 nM. LRRK2/NUAK1/TYK2-IN-1 can be used for autoimmune disease research[1].

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LSD1-IN-24 | MedChemExpress (MCE) 10 mM * 1 mL  | 99.20%

MedChem Express

LSD1-IN-24(compound 3S) is a selective LSD1 inhibitor with IC50 = 0.247 μM. LSD1-IN-24 can mediate the expression of PD-L1, enhance T cell killing response, and can be used in cancer research[1].

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LSD1-IN-24 | MedChemExpress (MCE) 5 mg  | 99.20%

MedChem Express

LSD1-IN-24(compound 3S) is a selective LSD1 inhibitor with IC50 = 0.247 μM. LSD1-IN-24 can mediate the expression of PD-L1, enhance T cell killing response, and can be used in cancer research[1].

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LSD1-IN-24 | MedChemExpress (MCE) 10 mg  | 99.20%

MedChem Express

LSD1-IN-24(compound 3S) is a selective LSD1 inhibitor with IC50 = 0.247 μM. LSD1-IN-24 can mediate the expression of PD-L1, enhance T cell killing response, and can be used in cancer research[1].

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LSD1-IN-24 | MedChemExpress (MCE) 25 mg  | 99.20%

MedChem Express

LSD1-IN-24(compound 3S) is a selective LSD1 inhibitor with IC50 = 0.247 μM. LSD1-IN-24 can mediate the expression of PD-L1, enhance T cell killing response, and can be used in cancer research[1].

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LSD1-IN-24 | MedChemExpress (MCE) 50 mg  | 99.20%

MedChem Express

LSD1-IN-24(compound 3S) is a selective LSD1 inhibitor with IC50 = 0.247 μM. LSD1-IN-24 can mediate the expression of PD-L1, enhance T cell killing response, and can be used in cancer research[1].

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LSD1-IN-24 | MedChemExpress (MCE) 100 mg  | 99.20%

MedChem Express

LSD1-IN-24(compound 3S) is a selective LSD1 inhibitor with IC50 = 0.247 μM. LSD1-IN-24 can mediate the expression of PD-L1, enhance T cell killing response, and can be used in cancer research[1].

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LSD1-IN-26 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

LSD1-IN-26 (compound 12u) is a potent LSD1 inhibitor, with an IC50 of 25.3 nM. LSD1-IN-26 also inhibits MAO-A (IC50=1234.57 nM) and MAO-B (IC50=3819.27 nM). LSD1-IN-26 significantly induces apoptosis in MGC-803 cells. LSD1-IN-26 can be used for gastric cancer research[1].

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LSD1-IN-27 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

LSD1-IN-27 (Compound 5ac) is a LSD1 inhibitor (IC50: 13 nM). LSD1-IN-27 inhibits the stemness and migration of gastric cancer cells. LSD1-IN-27 also reduces the expression of PD-L1 in BGC-823 and MFC cells. LSD1-IN-27 can enhance T cell immune response in gastric cancer[1].

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LSD1-UM-109 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

LSD1-UM-109 is a ighly potent and reversible LSD1 inhibitor with an IC50 of 3.1 nM. LSD1-UM-109 inhibits cell growth with IC50 values of 0.6 nM in the MV4;11 acute leukemia cell line and 1.1 nM in the H1417 small-cell lung cancer cell line[1].

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LSN3160440 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

LSN3160440 is an allosteric modulator of GLP-1R, which acts as a protein–protein interaction (PPI) stabilizer or molecular glue to assist in the adhesion of inactive GLP-1 (9-36) NH2 on GLP-1R[1][2].

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lsocryptomerin | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

lsocryptomerin is a membrane-active antifungal compound that can be isolated from Selaginella tamariscina. lsocryptomerin can depolarize fungal plasma membrane. lsocryptomerin also shows anticancer and antibacterial activities[1][2].

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lsocryptomerin | MedChemExpress (MCE) 5 mg  | ≥98.00%

MedChem Express

lsocryptomerin is a membrane-active antifungal compound that can be isolated from Selaginella tamariscina. lsocryptomerin can depolarize fungal plasma membrane. lsocryptomerin also shows anticancer and antibacterial activities[1][2].

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LSP-GR3 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

LSP-GR3 is a novel chemically-modified RNA oligonucleotides, called splice modulating oligomers (SMOs), which potently and specifically modulate GluR alternative splicing to GluR3-flip expression throughout the CNS.

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LSP-GR3 sodium | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

LSP-GR3 sodium is a novel chemically-modified RNA oligonucleotides, called splice modulating oligomers (SMOs), which potently and specifically modulate GluR alternative splicing to GluR3-flip expression throughout the CNS.

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LT-540-717 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

LT-540-717 (compound 32) is a potent FLT3 inhibitor (IC50=0.62 nM) with antiproliferative activity. LT-540-717 also inhibits several acquired FLT3 mutations, FLT3 (ITD, D835V), FLT3 (ITD, F691L), FLT3 (D835Y) and FLT3 (D835V). LT-540-717 has potential to be an anti-AML agent[1].

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LtaS-IN-2 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

LtaS-IN-2 (compound 13) is a inhibitor of LTA synthesis, and shows antibacterial activity against S. aureus and S. epidermidis, with the MIC90 of 0.5 μg/mL and 1 μg/mL, respectively. LtaS-IN-2 is a derivative of LtaS-IN-1 (HY-135813)[1].

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LTB4 antagonist 2 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

LTB4 antagonist 2, a carboxamide-acid compound, is an antagonist of leukotriene B4 (LTB4) with potentially anti-inflammatory activity. LTB4 antagonist 2 shows good affinity for the LTB4 receptor with IC50 of 439 nM[1].

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LTB4-IN-2 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

LTB4-IN-2 (Comopund 6x) is a Leukotriene B4 (LTB4) inhibitor. LTB4-IN-2 inhibits Leukotriene B4 formation (IC50: 1.15 μM) by selectively targeting 5-Lipoxygenase-activating protein (FLAP). LTB4-IN-2 can be used for anti-inflammatory research[1].

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Lu AA47070 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Lu AA47070 is a phosphonooxymethylene prodrug of a potent and selective Adenosine A2A receptor antagonist. Lu AA47070 reverses the motor and motivational effects produced by dopamine D2 receptor blockade[1][2].

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