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?-Apo-8′-carotenal (Apocarotenal), a provitamin A carotenoid, is an inducer of CYPlA1 and CYPlA2 in rat. ?-Apo-8′-carotenal is present in many fruits and vegetables.
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?-Chaconine inhibits the expressions of COX-2, IL-1?, IL-6, and TNF-? at the transcriptional level. ?-Chaconine inhibits the LPS-induced expressions of iNOS and COX-2 at the protein and mRNA levels and their promoter activities in RAW 264.7 macrophages. Anti-inflammatory effects.In Vitro: ?-Chaconine attenuates the transcriptional activity of activator protein-1 (AP-1) by reducing the translocation and phosphorylation […]
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?-Viniferin, the dimer of Resveratrol and isolated from Vitis vinifera, displays a potent inhibitory for all the CYP activities, with Ki values from 0.5-20 ?M. ?-Viniferin possesses potent antioxidant capacity[2].
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?-Amanitin is the principal toxin of several deadly poisonous mushrooms, exerting its toxic function by inhibiting RNA-polymerase II.IC50 & Target:ADCs cytotoxin, RNA-polymerase IIIn Vitro: ?-Amanitin decreases TAF15 mRNA and TAF15 protein levels in MKN45 cells, and inhibits the RNAPII activity towards TAF15 mRNA[2]. alpha-Amanitin decreases cell viability by 14%, 21%, 41%, 44%, and 50% at […]
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?-Amyloid (1-40) (rat) is a rat form of the amyloid ?-peptide, which accumulates as an insoluble extracellular deposit around neurons, giving rise to the senile plaques associated with Alzheimer’s disease (AD). ?-Amyloid (1-40) (rat) increases 45Ca2+ influx, induces neurodegeneration in the rat hippocampal neurons of the CA1 subfield. ?-Amyloid (1-40) (rat) induces apoptosis. ?-Amyloid (1-40) […]
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?-Amyloid (12-20) is a peptide fragment of ?-Amyloid.In Vitro:?-Amyloid Aggregation Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs). 1. Solid A? peptide was dissolved in cold hexafluoro-2-propanol (HFIP). The peptide was incubated at room temperature for at least 1h to establish monomerization […]
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?-Amyloid (12-28) (TFA) (Amyloid ?-Protein (12-28) (TFA)) is a peptide fragment of ?-amyloid protein (?1-42). ?1-42, a 42 amino acid protein , is the major component of senile plaque cores. ?-Amyloid (12-28) (TFA) shows aggregation properties. ?-Amyloid (12-28) (TFA) has the potential for Alzheimer’s disease research.In Vitro: ?-amyloid (12-28) may exert dysregulation cognitive effects by […]
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?-Anhydroicaritin is isolated from Boswellia carterii Birdware, has important biological and pharmacological effects, such as antiosteoporosis, estrogen regulation and antitumor properties. ?-Anhydroicaritin ameliorates the degradation of periodontal tissue and inhibits the synthesis and secretion of TNF-? and MMP-3 in diabetic rats[2]. ?-Anhydroicaritin decreases the overproduction of NO, IL-10, TNF-?, MCP-1 and IL-6 in inperitonitis mice. […]
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?-Arbutin (4-Hydroxyphenyl ?-D-glucopyranoside) is emerging as popular and effective skin whiteners, acting as tyrosinase inhibitor.
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?-Bungarotoxin is a competitive antagonist at nicotinic acetylcholine receptors (nAChRs). ?-Bungarotoxin, a selective ?7 receptor blocker, blocks ?7 currents with an IC50 of 1.6 nM and has no effects on ?3?4 currents at concentrations up to 3 ?M[2].In Vitro: ?-Bungarotoxin binds specifically and with high affinity to the nicotinic acetylcholine receptor and competes with binding […]
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?-Carrageenan (Viscarin SD 309) is a biochemical reagent. ?-Carrageenan can be isolated from Eucheuma serra or red algae H. musciformis and S. filiformis. ?-Carrageenan has potential application in protein emulsion flocculation and stability[2].In Vitro:?-Carrageenan (16.67-100% dispersed in mixture) containing films shows aggregation and low transparency.?-Carrageenan (0.088 wt% and 0.13 wt%) improves the droplet-size distributions of […]
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?-Carrageenan is a seaweed polysaccharide which has been generally used as proinflammatory agent in the basic research. ?-Carrageenan is a potent antitumor agent.In Vivo: ?-Carrageenan (50?mg/kg every two days; intratumoral injection) inhibits tumor growth in B16-F10 and 4T1 bearing mice. ?-carrageenan exhibits considerable antitumor effect via intratumoral injection and significantly improves the tumor immune response […]
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?-Conotoxin PIA TFA is a nicotinic acetylcholine receptor (nAChR) antagonist that targets nAChR subtypes containing ?6 and ?3 subunits. ?-Conotoxin PIA has the potential for the research of Parkinson’s disease, and schizophrenia?
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gamma-Cyclodextrin hydrate Vetec(TM) reagent grade is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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?-Cyfluthrin (beta-Cyfluthrin) is a type II synthetic pyrethroid and also an active ingredient of many insecticide products used for pestsin agriculture. ?-Cyfluthrin is a neurotoxicant and affects calcium concentration in nervous tissue by inhibiting Ca2+ ATPase involved in calcium transport.IC50 & Target: Target: Ca2+ ATPase
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?-D-glucopyranosyl-[?-L-rhamnopyranosyl-(1?3)-?D-glucuronopyranosyl-(1?3)]-3?-hydroxyolean-12-ene28-oate, as a saponin, has a glucuronic acid attached to carbon C-3 and is isolated from S. simplex.In Vitro: ?-D-glucopyranosyl-[?-L-rhamnopyranosyl-(1?3)-?D-glucuronopyranosyl-(1?3)]-3?-hydroxyolean-12-ene28-oate has a glucuronic acid attached to carbon C-3 and is isolated from S. simplex.
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?-D-Glucose-1-phosphate disodium hydrate is used as a starting material for synthesis of glucuronic acid. ?-D-Glucose-1-phosphate disodium hydrate can be used as a cytostatic compound essential for cardiopathic therapy, as an antibiotic, as an immunosuppressive drug, and as a circulatory system therapy element.
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