LP23 | MedChemExpress (MCE)

LP23 is a non-arylmethylamine PD-1/PD-L1 inhibitor (IC50: 16.7 nM) with anti-tumor activity. LP23 restores immune cell function in HepG2/Jurkat T cells and promotes HepG2 cell death. LP23 is active in vivo in the B16-F10 tumor model (TGI=88.6% at 30 mg/kg)[1].

Trivial name LP23
Catalog Number HY-156085
Research Area Cancer
Purity ≥98.00%
SMILES O=C([C@@H](NCC1=CC(CSC2=NN=C(COC3=C(C)C(C4=CC=CC=C4)=CC=C3)O2)=CC=C1)CO)O
PubChem Chemical Structure ID 168678270
Size 1 mg
Supplier Page https://www.medchemexpress.com/lp23.html