Creative Biolabs
Creative Biolabs
ADCs cytotoxin, 10-Deacetyl-7-xylosyl paclitaxel is a Paclitaxel derivative with ADCs cytotoxin,improved pharmacological features and higher water solubility.
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Creative Biolabs
ADCs cytotoxin, 10-Deacetyl-7-xylosyl paclitaxel is a Paclitaxel derivative with ADCs cytotoxin,improved pharmacological features and higher water solubility.
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Creative Biolabs
Creative Biolabs
ADCs linker, 6-Maleimidohexanoic acid N-hydroxysuccinimide ester(ECMS) is a useful protective group in antibody drug conjugates.
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Creative Biolabs
ADCs Toxins, 9-Hydroxyellipticine hydrochloride is a cell-permeable antitumor alkaloid that acts as a potent inhibitor of topoisomerase II. IC50=3.3 µM. Synthetic source.
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Creative Biolabs
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of BCR-ABL-derived peptide of GVRGRVEEI sequence A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
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Creative Biolabs
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of BCR-ABL-derived peptide of GVRGRVEEI sequence and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
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Creative Biolabs
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of EZH2-derived peptide of YMCSFLFNL sequence covering 666-674 and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
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Creative Biolabs
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of PSA-derived peptide of KLQCVDLHV sequence covering 146-154 and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
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Creative Biolabs
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of LY6K-derived peptide of RYCNLEGPPI sequence covering 177-186 and A*24:02 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
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Creative Biolabs
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of LY6K-derived peptide of RYCNLEGPPI sequence covering 177-186 and A*24:02 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
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Creative Biolabs
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of LY6K-derived peptide of RYCNLEGPPI sequence covering 177-186 and A*24:02 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
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Creative Biolabs
Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1). Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it is a homodimer of two […]
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Creative Biolabs
Abciximab is a Fab fragment of the chimeric human-murine monoclonal antibody 7E3. Abciximab binds to the glycoprotein (GP) IIb/IIIa receptor of human platelets and inhibits platelet aggregation by preventing the binding of fibrinogen, von Willebrand factor, and other adhesive molecules. It also binds to vitronectin (αvβ3) receptor found on platelets and vessel wall endothelial and […]
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Creative Biolabs
Adalimumab is a human monoclonal antibody against TNF-alpha. It is produced by recombinant DNA technology using a mammalian cell expression system. It consists of 1330 amino acids and has a molecular weight of approximately 148 kilodaltons.
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Creative Biolabs
Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. This recombinant form differs from native interleukin-2 in the following […]
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Creative Biolabs
Immunosuppressive dimeric fusion protein that consists of the extracellular CD2-binding portion of the human leukocyte function antigen-3 (LFA-3) linked to the Fc (hinge, CH2 and CH3 domains) portion of human IgG1. Produced by CHO cells, mW is 91.4 kD.
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Creative Biolabs
Human Beta-glucocerebrosidase or Beta-D-glucosyl-N-acylsphingosine glucohydrolase E.C. 3.2.1.45. 497 residue protein with N-linked carbohydrates, MW=59.3 kD. Alglucerase is prepared by modification of the oligosaccharide chains of human Beta-glucocerebrosidase. The modification alters the sugar residues at the non-reducing ends of the oligosaccharide chains of the glycoprotein so that they are predominantly terminated with mannose residues
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Creative Biolabs
Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.
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Creative Biolabs
Creative Biolabs
Creative Biolabs
ADCs Toxins, alpha-Amanitin, a cyclic peptide, consisting of eight amino acids.The source of this specific alpha-Amanitin is fungal fermentation. By this production method the supply problems are solved. alpha-Amanitin is an inhibitor of RNA polymerase II (0.02 micrograms/ml). RNA polymerase I was also inhibited by the relatively high concentration of alpha-amanitin (IC50 = 100 micrograms/ml […]
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Creative Biolabs
Creative Biolabs
Anakinra is a recombinant, nonglycosylated human interleukin-1 receptor antagonist (IL-1Ra). The difference between anakinra and the native human IL-1Ra is that anakinra has an extra methionine residue at the amino terminus. It is manufactured by using the E. coli expression system. Anakinra is composed of 153 amino acid residues. FDA approved on November 14, 2001.
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Creative Biolabs
Human tissue plasminogen activator, purified, glycosylated, 527 residues purified from CHO cells. Eminase is a lyophilized (freeze-dried) formulation of anistreplase, the p-anisoyl derivative of the primary Lys-plasminogen-streptokinase activator complex (a complex of Lys-plasminogen and streptokinase). A p-anisoyl group is chemically conjugated to a complex of bacterial-derived streptokinase and human Plasma-derived Lys-plasminogen proteins.
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Creative Biolabs
ADCs cytotoxin, Ansamitocin P-3, a potent anti-tumor maytansinoid found in Actinosynnema pretiosum, is a maytansine analog which displays potent cytotoxicity against the human solid tumor cell lines A-549 and HT-29.
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Creative Biolabs
Equipped with world-leading technology platforms in antibody development and antimicrobial peptides (AMPs) discovery, Creative Biolabs has rich experience in antibody and AMP discovery for bacterial disease.
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Creative Biolabs
Creative Biolabs is dedicated to providing our customers with high-quality antibody and peptide discovery service for diagnostic and therapeutic proposes.
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Creative Biolabs
Creative Biolabs has accumulated over a decade of experience in antibody development and antimicrobial peptides (AMPs) discovery for viral disease. https://www.creative-biolabs.com/antinfect/antibody-peptide-discovery-for-viral-disease.htm
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Creative Biolabs
Therapeutic proteins are proteins that are engineered in the laboratory for pharmaceutical use, including noncovalent binders, proteins that affect covalent bonds which are almost all enzymes, and albumin.
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Creative Biolabs
Reduced Fab fragment of the murine IgG1 monoclonal antibody IMMU-4 (also called NP-4) with specificity for carcinoembryonic antigen (CEA) covalently labeled with Technitium 99. The molecule has a molecular weight of ~54,000 Daltons.
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Creative Biolabs
Creative Biolabs
ADCs cytotoxin, Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAE analog and cytotoxin in Antibody-drug conjugates.
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Creative Biolabs
ADCs cytotoxin, Auristatin F is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAF analog and cytotoxin in Antibody-drug conjugates.
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Creative Biolabs
A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also known as CD25 antigen) on the surface of activated T-lymphocytes. It is a 144 kDa glycoprotein obtained from fermentation of an established mouse myeloma cell line genetically engineered to express […]
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Creative Biolabs
Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet derived growth factor (PDGF) into the yeast, Saccharomyces cerevisiae. Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical polypeptide chains that are bound together by disulfide bonds.
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Creative Biolabs
ADCs Toxins, beta-Amanitin, a cyclic peptide, consisting of eight amino acids is part of the toxic peptide group of the Amanita phalloides mushroom. beta-Amanitin inhibits mammalian protein synthesis.It is an inhibitor of RNA polymerase II and III but not RNA polymerase I or bacterial RNA polymerase.
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Creative Biolabs
A recombinant humanized monoclonal IgG1 antibody that binds to and inhibits the biologic activity of human vascular endothelial growth factor (VEGF). Bevacizumab contains human framework regions and the complementarity-determining regions of a murine antibody that binds to VEGF. Bevacizumab is produced in a Chinese Hamster Ovary mammalian cell expression system in a nutrient medium containing […]
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Creative Biolabs
Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin. Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is administered intravenously. Because it can cause blood stagnation, it is important to monitor changes in hematocrit, activated partial thromboplastin time, […]
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Creative Biolabs
Creative Biolabs
Neurotoxin produced by fermentation of clostridium botulinum type B. The protein exists in noncovalent association with hemagglutinin and nonhemagglutinin proteins as a neurotoxin complex. The neurotoxin complex is recovered from the fermentation process and purified through a series of precipitation and chromatography steps.
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Creative Biolabs