A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also known as CD25 antigen) on the surface of activated T-lymphocytes. It is a 144 kDa glycoprotein obtained from fermentation of an established mouse myeloma cell line genetically engineered to express plasmids containing the human heavy and light chain constant region genes and mouse heavy and light chain variable region genes encoding the RFT5 antibody that binds selectively to the IL-2R alpha.

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Trivial name IGHG1
Catalog Number TP-094CL
Alternative Name(s) Basiliximab
Research Area Transplantation
Molecular Formula C6378H9844N1698O1997S48
CAS# 179045-86-4
Purity >90%
Size 1 mg
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Additional Information For prophylactic treatment of kidney transplant rejection