Creative Biolabs

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Creative Biolabs is a leading company of recombinant antibody (rAb) discovery and manufacturing, providing high quality service to customers in academia and industry fields all over the world. Our cutting-edge hybridoma development and phage display platforms allow the production of the most comprehensive list of recombinant antibody products and extensive service portfolio at the most competitive price.

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Daunorubicin 1 mg  | >95%

Creative Biolabs

ADCs cytotoxin, Daunorubicin(RP13057) inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM.

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Daunorubicin HCl 1 mg  | >95%

Creative Biolabs

ADCs Toxins, Daunorubicin HCl is a chemotherapeutic of the anthracycline family. It is mainly used to treat acute myeloid leukemia and acute lymphocytic leukemia. The biochemical mode of action is the inhibition of DNA and RNA synthesis as sequence specific ds-DNA interacting agent. Daunomycin binds to every 3 base pairs and induces a local unwinding […]

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Denileukin diftitox 1 mg  | >90%

Creative Biolabs

A recombinant DNA-derived cytotoxic protein composed of the amino acid sequences for diphtheria toxin fragments A and B (Met 1-Thr 387)-His followed by the sequences for interleukin-2 (IL-2; Ala 1-Thr 133). It is produced in an E. coli expression system.

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DL-Dithiothreitol/DTT 1 mg  | >95%

Creative Biolabs

ADCs Toxins, Used in molecular biology. DTT preserves proteins of interiors of cells in their functional form by avoiding the oxidation of Sulfhidril-groups (SH-) into disulifidbridges through atmospheric oxygen. On the other hand the convolution of proteins whose structure is stabilised by disulfidbridges may be destroyed by their reduction. It is an important reagent in […]

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DL-Dithiothreitol/DTT – biotech grade 1 mg  | >95%

Creative Biolabs

ADCs Toxins, Used in molecular biology. DTT preserves proteins of interiors of cells in their functional form by avoiding the oxidation of Sulfhidril-groups (SH-) into disulifidbridges through atmospheric oxygen. On the other hand the convolution of proteins whose structure is stabilised by disulfidbridges may be destroyed by their reduction. It is an important reagent in […]

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DL-Dithiothreitol/DTT – pure grade 1 mg  | >95%

Creative Biolabs

ADCs Toxins, Used in molecular biology. DTT preserves proteins of interiors of cells in their functional form by avoiding the oxidation of Sulfhidril-groups (SH-) into disulifidbridges through atmospheric oxygen. On the other hand the convolution of proteins whose structure is stabilised by disulfidbridges may be destroyed by their reduction. It is an important reagent in […]

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DM1 1 mg  | >95%

Creative Biolabs

ADCs Toxins, DM1 belongs to Maytansinoids which are a group of cytotoxins structurally similar to rifamycin, geldanamycin, and ansatrienin. Maytansinoids can bind to tubulin at or near the vinblastine-binding site, which interfere the formation of microtubules and depolymerize already formed microtubules, inducing mitotic arrest in the intoxicated cells.

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DM4 1 mg  | >95%

Creative Biolabs

ADCs Toxins, DM4 belongs to Maytansinoids which are a group of cytotoxins structurally similar to rifamycin, geldanamycin, and ansatrienin. Maytansinoids can bind to tubulin at or near the vinblastine-binding site, which interfere the formation of microtubules and depolymerize already formed microtubules, inducing mitotic arrest in the intoxicated cells.

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Dolastatin 10 1 mg  | >95%

Creative Biolabs

ADCs cytotoxin, Dolastatin 10 is a potent antimitotic peptide from a marine animal, strongly inhibits microtubule assembly.

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Dolastatin 15 1 mg  | >95%

Creative Biolabs

ADCs Toxins, Dolastatin 15 may be a useful tubulin-targeting payload for the conjugation at various antibody reactive sites, depending on the used linker technology. IC50 value 23 µM (Bai et al. 1992). Dolastatin 15 is a Tubulin inhibitor.

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Dornase alfa 1 mg  | >90%

Creative Biolabs

Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products without affecting […]

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DOXO-EMCH 1 mg  | >95%

Creative Biolabs

Linker-Toxin SET, INNO-206 (Aldoxorubicin) is the 6-maleimidocaproyl hydrazone derivative prodrug of the anthracycline antibiotic doxorubicin (DOXO-EMCH) with antineoplastic activity. Following intravenous administration, doxorubicin prodrug INNO-206 binds selectively to the cysteine-34 position of albumin via its maleimide moiety.

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Doxorubicin 1 mg  | >95%

Creative Biolabs

ADCs cytotoxin, Doxorubicin(Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.

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Drotrecogin alfa 1 mg  | >90%

Creative Biolabs

Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and a light chain linked by a disulfide bond. Drotrecogin alfa was withdrawn from the market after a major study indicated that it was not effective […]

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Duocarmycin SA 1 mg  | >95%

Creative Biolabs

ADCs Toxins, Duocarmycins, which were first isolated from Streptomyces bacteria in 1988, have shown activity in a variety of multi-drug resistant (MDR) models. Agents that are part of this class of duocarmycins have the potency in the low picomolar range. This makes them suitable for maximizing the cell-killing potency of antibody-drug conjugates to which they […]

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Eculizumab 1 mg  | >90%

Creative Biolabs

Soliris is a formulation of eculizumab which is a recombinant humanized monoclonal IgG2/4;κ antibody produced by murine myeloma cell culture and purified by standard bioprocess technology. Eculizumab contains human constant regions from human IgG2 sequences and human IgG4 sequences and murine complementarity-determining regions grafted onto the human framework light- and heavy-chain variable regions. Eculizumab is […]

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Efalizumab 1 mg  | >90%

Creative Biolabs

Humanized IgG1 kappa isotype monoclonal antibody that binds to human CD11a. Efalizumab has a molecular weight of approximately 150 kilodaltons and is produced in a Chinese hamster ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin.

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Enfuvirtide 1 mg  | >90%

Creative Biolabs

Enfuvirtide is a 36 residue synthetic peptide that inhibits HIV-1 fusion with CD4 cells. It is an N-terminal acetylated, C-terminal amide. As an HIV fusion inhibitor, it is the first of a novel class of antiretroviral drugs used in combination therapy for the treatment of HIV-1 infection.

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Epothilone B 1 mg  | >95%

Creative Biolabs

ADCs Toxins, Microtubule stabilization agent that promotes tubulin polymerization and induces G2-M cell cycle arrest. Inhibits a variety of human cancer cell lines, including MDR cells overexpressing the P-glycoprotein efflux pump. Exhibits potent anticancer activity in numerous human tumor xenografts in vivo. Epothilone B is a Tubulin inhibitor.

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epsilon-Amanitin 1 mg  | >95%

Creative Biolabs

ADCs Toxins, epsilon-Amanitin is a cyclic peptide, found i.e. in the Amanita genus of mushrooms. Oral LD50 is in the range of 0.1 mg/kg.

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Etanercept 1 mg  | >90%

Creative Biolabs

Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1. Etanercept is produced by recombinant […]

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Exenatide 1 mg  | >90%

Creative Biolabs

Exenatide, derived from a compound found in the saliva of the Gila monster, a large lizard native to the southwestern US, is a functional analog of Glucagon-Like Peptide-1 (GLP-1), a naturally occuring peptide.

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Ferulenol 1 mg  | >95%

Creative Biolabs

ADCs Toxins, Ferulenol is an cytotoxic Anti-tumor compound. Ferulenol inhibits the colchicine binding to tubulin. It is an Antitubercular antibiotic with potent antibacterial activity. Ferulenol is isolated from Ferula communis.

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Filgrastim 1 mg  | >90%

Creative Biolabs

Filgrastim is a recombinant, non-pegylated human granulocyte colony stimulating factor (G-CSF) analogue manufactured by recombinant DNA technology using a strain of E. coli. It is marketed as the brand name Neupogen by Amgen. Chemically, it consists of 175 amino acid residues. The protein has an amino acid sequence that is identical to the natural sequence […]

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Follitropin beta 1 mg  | >90%

Creative Biolabs

Follitropin beta is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51 and Asn 78 while the beta subunit […]

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Fumagillin 1 mg  | >95%

Creative Biolabs

ADCs Toxins, Fumagillin is a methionine aminopeptidase-2 (MetAP-2) inhibitor; Fumagillin inhibits endothelial cell proliferation and angiogenesis. Fumagillin belongs to the group of mycotoxins. Origin: Aspergillus fumigatus

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Galsulfase 1 mg  | >90%

Creative Biolabs

Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant DNA origin. Galsulfase is a glycoprotein with a molecular weight of approximately 56 kD. The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation sites, four of which carry a bis mannose-6-phosphate manose7 oligosaccharide for specific cellular […]

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Geldanamycin 1 mg  | >95%

Creative Biolabs

ADCs Toxins, Geldanamycin is a benzoquinone ansamycin antibiotic. Geldamycin is among other things used to cure cancer patients. It specifically ties up to the heat shock proteine HSP 90 (Heat Shock Protein 90) and changes its function. The bond of Geldamycin to HSP 90 causes the decomposition of target-proteins such as Tyrosinkinasen, Steroidrezeptoren, Transkriptionsfactors and […]

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Gemtuzumab ozogamicin 1 mg  | >90%

Creative Biolabs

Recombinant humanized IgG4, kappa antibody conjugated with a cytotoxic antitumor antibiotic, calicheamicin, isolated from fermentation of a bacterium, Micromonospora echinospora ssp. calichensis. The antibody portion of Mylotarg binds specifically to the CD33 antigen, The anti-CD33 hP67.6 antibody is produced by mammalian cell suspension culture using a myeloma NS0 cell line. Gemtuzumab ozogamicin (trade name Mylotarg) […]

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Glucagon recombinant 1 mg  | >90%

Creative Biolabs

29 residue peptide hormone. Glucagon is synthesized in a special non- pathogenic laboratory strain of Escherichia coli bacteria that has been genetically altered by the addition of the gene for glucagons

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Glucopiericidin A 1 mg  | >95%

Creative Biolabs

ADCs Toxins, Glucopiericidin A is a natural bioactive compound. Glucopiericidin A (GPA) interestingly alone did not inhibit filopodia protrusion, but synergistically inhibit protrusion with the mitochondrial respiration inhibitor, piericidin A (PA). These results suggested that GPA might inhibit glycolysis. GPA may therefore serve as a glucose transporter chemical probe. Simultaneous inhibition of both glycolysis and […]

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Gramicidin A 1 mg  | >95%

Creative Biolabs

ADCs Toxins, Amino Acid Sequence: HCO-X-Gly-L-Ala-D-Leu-L-Ala-D-Val-L-Val-D-Val-L-Trp-D-Leu-L-Trp-D-Leu-L-Trp-D-Leu-L-Trp-NHCH2CH2OH – Gramicidin A is a polypeptide antibiotic that forms single ion monovalent cation channels in biological membranes. Gramicidin A increases the permeability of bacterial cell membranes which allows inorganic monovalent cations to travel through unrestricted. This destroys the ion gradient between the cytoplasm and the extracellular environment. HCT-116: IC50=0,44 […]

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Herboxidiene 1 mg  | >95%

Creative Biolabs

ADCs Toxins, Herboxidiene is described as a microbial product with antitumor activity. Herboxidiene seems to serve as a novel splicing inhibitor that specifically impairs the SF3b function by binding to SAP155. Herboxidiene in house activity data obtained from our manufacturing partner: Cellular line A549 (lung cander) IC50: 0,036 ug/ml – IC50 82 uM; Cellular line […]

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Histrelin 1 mg  | >90%

Creative Biolabs

Therapeutic proteins are proteins that are engineered in the laboratory for pharmaceutical use, including noncovalent binders, proteins that affect covalent bonds which are almost all enzymes, and albumin.

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Hygrolidin 1 mg  | >95%

Creative Biolabs

ADCs Toxins, Hygrolidin is a macrocyclic lactone closely related to the group of bafilomycins. Hygrolidin is active against Valsa ceratosperma, the pathogen of an apple desease called “canker disease”. Hygrolidin is active against SV40 tumour cells, and inhibits the growth of solid tumour-derived cell lines.HCT-116: IC50=0,0014 uM; PSN1 : IC50=0,72 uM; T98G : IC50=1,447 uM; […]

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Hypothemycin 1 mg  | >95%

Creative Biolabs

ADCs Toxins, Exhibits antifungal and cytotoxic activity against some tumor cell lines partly attributed to inhibition of Ras-inducible genes. Inhibits proliferation of mouse and human T cells and modulates production of cytokines during T cell activation. Facilitates the ubiquitinylation process of cyclin D1. Has been identified as a potent and selective inhibitor of threonine/tyrosine-specific kinase, […]

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Ibritumomab tiuxetan 1 mg  | >90%

Creative Biolabs

Indium or yttrium conjugated murine IgG1 kappa monoclonal antibody directed against the CD20 antigen, which is found on the surface of normal and malignant B lymphocytes. Ibritumomab is produced in Chinese hamster ovary cells and is composed of two murine gamma 1 heavy chains of 445 amino acids each and two kappa light chains of […]

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Idursulfase 1 mg  | >90%

Creative Biolabs

Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. Idursulfase is produced by recombinant DNA technology in a human cell line. Idursulfase is an enzyme that hydrolyzes the 2-sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and heparan sulfate in the lysosomes of various cell types. Idursulfase is a […]

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Ilimaquinone 1 mg  | >95%

Creative Biolabs

ADCs Toxins, Ilimaquinone is a cell permeable, antimicrobial, anti-inflammatory, antimitotic and cytotoxic compound.

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Imiglucerase 1 mg  | >90%

Creative Biolabs

Human Beta-glucocerebrosidase or Beta-D-glucosyl-N-acylsphingosine glucohydrolase E.C. 3.2.1.45. 497 residue protein with N-linked carbohydrates, MW=59.3 kD. Alglucerase is prepared by modification of the oligosaccharide chains of human Beta-glucocerebrosidase. The modification alters the sugar residues at the non-reducing ends of the oligosaccharide chains of the glycoprotein so that they are predominantly terminated with mannose residues

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