Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. This recombinant form differs from native interleukin-2 in the following ways: a) Aldesleukin is not glycosylated because it is derived from E. coli; b) the molecule has no N-terminal alanine; the codon for this amino acid was deleted during the genetic engineering procedure; c) the molecule has serine substituted for cysteine at amino acid position 125.

Price Not Available 1 mg Aldesleukin Supplier Page
Trivial name IL2
Catalog Number TP-046CL
Alternative Name(s) Aldesleukin
Research Area Immunoregulation
Molecular Formula C690H1115N177O202S6
CAS# 85898-30-2
Purity >90%
Size 1 mg
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Additional Information For treatment of adults with metastatic renal cell carcinoma.