Creative Biolabs is a leading company of recombinant antibody (rAb) discovery and manufacturing, providing high quality service to customers in academia and industry fields all over the world. Our cutting-edge hybridoma development and phage display platforms allow the production of the most comprehensive list of recombinant antibody products and extensive service portfolio at the most competitive price.
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ADCs Toxins, Isofistularin-3 is a natural, marine alkaloid belonging to the group of bromotyrosine-derivatives. It is a cytotoxic isoxazoline compound. Isofistularin-3 shows in vitro activity against HeLa cells. It has shown antiproliferative activities against Jurkat and U937 cellts (MTT-Assay).
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ADCs Toxins, Ixabepilone is an epothilone B analog and microtubule-stabilizing agent. Ixabepilone showed potent induction of tubulin polymerization with an EC50 value of 3.5 µM
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ADCs Toxins, JW 55 is an inhibitor of the PARP domain of tankyrase 1 and 2 (TNKS1/2). The JW 55 activity results in stabilization of Axin2 and increased degradation of β-catenin.It inhibits the β-catenin signaling pathway. JW 55 has also shown to decrease canonical Wnt signaling in SW480 and HCT-15 colon carcinoma cell lines.
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ADCs Toxins, Lactacystin is a cell-permeable, potent and selective proteasome inhibitor. A Streptomyces metabolite that is thought to bind irreversibly to the active site N-terminal threonine residue of the catalytic β-subunit of the 20S proteasome, thereby inhibiting its chymotrypsin and trypsin-like activities. Lactacystin induces neurite outgrowth in Neuro 2a neuroblastoma cells and has been reported […]
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Lepirudin is identical to natural hirudin except for substitution of leucine for isoleucine at the N-terminal end of the molecule and the absence of a sulfate group on the tyrosine at position 63. It is produced via yeast cells. Bayer ceased the production of lepirudin (Refludan) effective May 31, 2012.
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ADCs Toxins, Luisol A shows weak cytotoxic activities against tumor cell lines. Luisol A has antiparasitic activity.
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Lutropin alfa is a recombinant human luteinizing hormone produced in yeast with 2 subunits, alpha = 92 residues, beta = 121 residues. It is a heterodimeric glycoprotein. Each monomeric unit is a glycoprotein molecule. In females, an acute rise of LH (“LH surge”) triggers ovulation and the development of the corpus luteum. In males, it […]
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Lyophilized Exosomes can be used as control standards for multiple applications including FACS, WB, ELISA and as calibration standards for quantitation of exosome-derived markers from biological samples. Lyophilized exosomes can be obtained from a variety of biological sources including cell culture supernatant, human plasma, serum, urine and saliva.
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Lyophilized Exosomes can be used as control standards for multiple applications including FACS, WB, ELISA and as calibration standards for quantitation of exosome-derived markers from biological samples. Lyophilized exosomes can be obtained from a variety of biological sources including cell culture supernatant, human plasma, serum, urine and saliva.
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Lyophilized Exosomes can be used as control standards for multiple applications including FACS, WB, ELISA and as calibration standards for quantitation of exosome-derived markers from biological samples. Lyophilized exosomes can be obtained from a variety of biological sources including cell culture supernatant, human plasma, serum, urine and saliva.
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Lyophilized Exosomes can be used as control standards for multiple applications including FACS, WB, ELISA and as calibration standards for quantitation of exosome-derived markers from biological samples. Lyophilized exosomes can be obtained from a variety of biological sources including cell culture supernatant, human plasma, serum, urine and saliva.
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Lyophilized Exosomes can be used as control standards for multiple applications including FACS, WB, ELISA and as calibration standards for quantitation of exosome-derived markers from adipose mesenchymal stem cells samples. Compared with fresh exosomes, freeze-drying does not change the stability of exosomes protein and nucleic acid, but it is easy to transport and store for […]
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Lyophilized Exosomes can be used as control standards for multiple applications including FACS, WB, ELISA and as calibration standards for quantitation of exosome-derived markers from bovine milk samples. Compared with fresh exosomes, freeze-drying does not change the stability of exosomes protein and nucleic acid, but it is easy to transport and store for a long […]
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Lyophilized Exosomes can be used as control standards for multiple applications including FACS, WB, ELISA and as calibration standards for quantitation of exosome-derived markers from endodontium mesenchymal stem cells samples. Compared with fresh exosomes, freeze-drying does not change the stability of exosomes protein and nucleic acid, but it is easy to transport and store for […]
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Lyophilized Exosomes can be used as control standards for multiple applications including FACS, WB, ELISA and as calibration standards for quantitation of exosome-derived markers from placental amniotic mesenchymal stem cells samples. Compared with fresh exosomes, freeze-drying does not change the stability of exosomes protein and nucleic acid, but it is easy to transport and store […]
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Lyophilized Exosomes can be used as control standards for multiple applications including FACS, WB, ELISA and as calibration standards for quantitation of exosome-derived markers from umbilical cord mesenchymal stem cells samples. Compared with fresh exosomes, freeze-drying does not change the stability of exosomes protein and nucleic acid, but it is easy to transport and store […]
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ADCs Toxins, A maytansinoid is a chemical derivative of maytansine being investigated as the cytotoxic component of antibody-drug conjugates. Anticancer properties of maytansinoids have been attributed to their ability to disrupt microtubule function.
More Information Supplier PageADCs cytotoxin, Maytansinol inhibits microtubule assembly and induces microtubule disassembly in vitro.
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Linker-Toxin SET, Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate; Mc-MMAD is a protective group (maleimidocaproyl) -conjugated MMAD.
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Linker-Toxin SET, Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate; Mc-MMAE is a protective group (maleimidocaproyl) -conjugated MMAE.
More Information Supplier PageLinker-Toxin SET, Monomethylauristatin F(MMAF) is an antitubulin agent that inhibit cell division by blocking the polymerization of tubulin; lower cytotoxic activity than MMAE; Mc-MMAF is a protective group (maleimidocaproyl) -conjugated MMAF.
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ADCs linker, Mc-Val-Cit-PAB-PNP is a cathepsin cleavable linker for antibody-drug-conjugation (ADC).
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ADCs linker, Mc-Val-Cit-PABC-PNP is a cathepsin cleavable ADC peptide linker.
More Information Supplier PageLinker-Toxin SET, This set is made by MMAE conjugated to MC-vc-PAB linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate.
More Information Supplier PageMecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1). IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons. The amino acid sequence of the product is identical to that of endogenous human IGF-1. The rhIGF-1 protein is synthesized in bacteria (E. coli) that […]
More Information Supplier PageMecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1). IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons. The amino acid sequence of the product is identical to that of endogenous human IGF-1. The rhIGF-1 protein is synthesized in bacteria (E. coli) that […]
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ADCs Toxins, Mechercharmycin A is a cytotoxic compound with antitumor activitiy. It is a marine-derived Thermoactinomyces sp. HCT-116: IC50=0,0014 µM; PSN1 : IC50=0,007 µM; T98G : IC50=0,014 µM; A549 : IC50=0,007 µM (preliminary laboratory results). Journal of Antibiotics (2005), 58(4), 289-292.
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ADCs Toxins, Mensacarcin is an antitumor compund. Mensacarcin has cytotoxic activity (TGI 1.3 µM, NCI standard). Furthermore Mensacarcin is described as an antibiotic compound. Mensacarcin is isolated from Streptomyces bottropensis
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ADCs Toxins, Microcystin LR is a cyclic heptapeptide produced by the species of cyanobacteria Microcystis. Microcystin exhibits cytotoxic, carcinogenic and pro-oxidateive properties.
More Information Supplier PageADCs cytotoxin, Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload and antibody drug conjugate.
More Information Supplier PageADCs cytotoxin, Monomethyl auristatin D Hcl (MMAD Hcl), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate.
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