Mecasermin
Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1). IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons. The amino acid sequence of the product is identical to that of endogenous human IGF-1. The rhIGF-1 protein is synthesized in bacteria (E. coli) that have been modified by the addition of the gene for human IGF-1.
| Trivial name | Mecasermin |
| Catalog Number | TP-009CL |
| Alternative Name(s) | Mecasermin |
| Research Area | Endocrine disorders (hormone deficiencies) |
| Molecular Formula | C331H518N94O101S7 |
| CAS# | 68562-41-4 |
| Purity | >90% |
| Size | 1 mg |
| Supplier Page | https://www.creativebiolabs.net/Mecasermin-22347.htm |
| Additional Information | For the long-term treatment of growth failure in pediatric patients with Primary IGFD or with GH gene deletion who have developed neutralizing antibodies to GH. It is not indicated to treat Secondary IGFD resulting from GH deficiency, malnutrition, hypothyroidism or other causes; it is not a substitute for GH therapy. |