AdipoGen Life Sciences

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AdipoGen Life Sciences develops and manufactures new products for the Life Science Research Market in the key areas of cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cell biology, and neurodegeneration. The product portfolio consists of antibodies, proteins, ELISA Kits and innovative small molecules. The chemical portfolio includes, rare antibiotics, unique natural products, synthetic kinase modulators, fluorescent probes and much more.

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SIN-1 chloride 50 mg  | >98%

AdipoGen Life Sciences

Nitric oxide (NO) donor. Generates both superoxide anion and nitric oxide that spontaneously form peroxynitrite. Platelet aggregation inhibitor. Guanylyl cyclase activator. Cytotoxic. Positive ionotropic. Vasodilator.

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Sipholenol A 100 µg  | >98%

AdipoGen Life Sciences

Efficient inhibitor of P-glycoprotein (Pgp, MDR-1) function through direct interactions. By inhibiting MDR-1, active compounds remain in the cytoplasm longer and allowing them to be more effective within the cell. Reversing agent for the treatment of multidrug resistance (MDR) in Pgp-overexpressing tumors. Potentiates the cytotoxicity of established P-gp substrates such as colchicine, vinblastine and paclitaxel. […]

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Sipholenone A 100 µg  | >98%

AdipoGen Life Sciences

Efficient inhibitor of P-glycoprotein (Pgp, MDR-1) function through direct interactions. By inhibiting MDR-1, active compounds remain in the cytoplasm longer and allowing them to be more effective within the cell. Reversing agent for the treatment of multidrug resistance (MDR) in Pgp-overexpressing tumors. Potentiates the cytotoxicity of established P-gp substrates such as colchicine, vinblastine and paclitaxel. […]

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Sirtinol 1 mg  | >98%

AdipoGen Life Sciences

Specific cell permeable SIRT1 (sirtuin 1) inhibitor. Senescence-like growth arrest inducer. Platelet aggregation inhibitor. Apoptosis inducer.

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Sirtinol 5 mg  | >98%

AdipoGen Life Sciences

Specific cell permeable SIRT1 (sirtuin 1) inhibitor. Senescence-like growth arrest inducer. Platelet aggregation inhibitor. Apoptosis inducer.

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Sirtinol 25 mg  | >98%

AdipoGen Life Sciences

Specific cell permeable SIRT1 (sirtuin 1) inhibitor. Senescence-like growth arrest inducer. Platelet aggregation inhibitor. Apoptosis inducer.

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Skyrin 5 mg  | >98%

AdipoGen Life Sciences

Mycotoxin. Antibiotic (incl. MRSA). Non-peptidic anti-diabetic agent (receptor-selective glucagon antagonist). Inhibitor of botulinum neurotoxin serotype A (BoNTA). Cytotoxic. Antioxidant (free radical scavenger).

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Skyrin 1 mg  | >97%

AdipoGen Life Sciences

Non-peptidic anti-diabetic agent. Receptor-selective glucagon antagonist. Free radical species (·OH, R·) and singlet oxygen (1O2) scavenger. Mycotoxin. Cytotoxic. Antioxidant. Inhibitor of botulinum neurotoxin serotype A (BoNTA). Anti-MRSA compound. Antibiotic.

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SMI-4a 5 mg  | >95%

AdipoGen Life Sciences

Selective inhibitor of Pim-1 and Pim-2 protein kinases. Inducer of G1 phase cell cycle arrest. Inducer of p27Kip1. Inducer of apoptosis through the mitochondrial pathway. Inhibitor of the mammalian target of rapamycin C1 (mTORC1) pathway. Downregulates c-myc. Inhibitor of PRAS40 phosphorylation and mTOR activity. Potential anti-cancer compound. Blocks prostate cancer growth.

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SNARF-DE 10 mg  | >95%

AdipoGen Life Sciences

Lipophilic fluorescent pH indicator used to assay biogenic amines with optodes. The deprotonated version enables excitation with red light (LED) (Ex/Em: 605/680nm) versus the acidic form (Ex/Em: 520/600nm). The ester functionality renders the indicator molecule lipophilic and water-insoluble but also prevents lactonization of the dye in an apolar environment.

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SNARF-DE 50 mg  | >95%

AdipoGen Life Sciences

Lipophilic fluorescent pH indicator used to assay biogenic amines with optodes. The deprotonated version enables excitation with red light (LED) (Ex/Em: 605/680nm) versus the acidic form (Ex/Em: 520/600nm). The ester functionality renders the indicator molecule lipophilic and water-insoluble but also prevents lactonization of the dye in an apolar environment.

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SNC80 5 mg  | >99%

AdipoGen Life Sciences

Highly selective and potent non-peptide delta-opioid receptor agonist. Mediates downregulation of the delta-opioid receptor. Shows antidepressant-like effects. Modulates voltage-dependent sodium channels. Antinociceptive. Activates ATP-sensitive K+ channels. Enhances amphetamine-mediated dopamine efflux.

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SNC80 25 mg  | >99%

AdipoGen Life Sciences

Highly selective and potent non-peptide delta-opioid receptor agonist. Mediates downregulation of the delta-opioid receptor. Shows antidepressant-like effects. Modulates voltage-dependent sodium channels. Antinociceptive. Activates ATP-sensitive K+ channels. Enhances amphetamine-mediated dopamine efflux.

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Sorbic chloride 1 g  | >90%

AdipoGen Life Sciences

Reactant for: (1) preparation of unsaturated hydroxymethylene diphosphonic acid derivatives by reaction of trimethylsilyl phosphites, (2) asymmetrical synthesis of the isoindolinone subunit of the macrocyclic poylketide natural product muironolide via stereoselective intramolecular Diels-Alder cycloaddition, (3) preparation of emollient, humectant, and fluorescent alpha,beta-unsaturated thiol esters for long-acting skin applications, (4) stereoselective synthesis of enediol carbonates for […]

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Sorbic chloride 5 g  | >90%

AdipoGen Life Sciences

Reactant for: (1) preparation of unsaturated hydroxymethylene diphosphonic acid derivatives by reaction of trimethylsilyl phosphites, (2) asymmetrical synthesis of the isoindolinone subunit of the macrocyclic poylketide natural product muironolide via stereoselective intramolecular Diels-Alder cycloaddition, (3) preparation of emollient, humectant, and fluorescent alpha,beta-unsaturated thiol esters for long-acting skin applications, (4) stereoselective synthesis of enediol carbonates for […]

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Splitomicin 1 mg  | >98%

AdipoGen Life Sciences

Potent cell permeable and selective inhibitor of yeast NAD+-dependent histone deacetylase (HDAC) Sir2p. Displays higher activity in vivo than in vitro. Sensitizes mammalian cells to a variety of DNA-damaging agents by abrogating Sir2p activity on p53. Acts by either altering or blocking access to the acetylated histone binding pocket. Shown to have diverse effects also […]

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Splitomicin 5 mg  | >98%

AdipoGen Life Sciences

Potent cell permeable and selective inhibitor of yeast NAD+-dependent histone deacetylase (HDAC) Sir2p. Displays higher activity in vivo than in vitro. Sensitizes mammalian cells to a variety of DNA-damaging agents by abrogating Sir2p activity on p53. Acts by either altering or blocking access to the acetylated histone binding pocket. Shown to have diverse effects also […]

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Splitomicin 25 mg  | >98%

AdipoGen Life Sciences

Potent cell permeable and selective inhibitor of yeast NAD+-dependent histone deacetylase (HDAC) Sir2p. Displays higher activity in vivo than in vitro. Sensitizes mammalian cells to a variety of DNA-damaging agents by abrogating Sir2p activity on p53. Acts by either altering or blocking access to the acetylated histone binding pocket. Shown to have diverse effects also […]

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Staurosporine 100 µg  | >98%

AdipoGen Life Sciences

Antibiotic. Antifungal and anti-yeast activity. Inhibits platelet aggregation induced by collagen or ADP. Has no effect on thrombin-induced platelet aggregation. Potent, cell permeable, reversible, ATP-competitive and broad spectrum inhibitor of protein kinases. Inhibits protein kinase A, CaM kinase, myosin light chain kinase, protein kinase C, protein kinase G, CDK1/cyclin B, CDK2/cyclin A, CDK4/cyclin D, CDK5/p25, […]

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Staurosporine 500 µg  | >98%

AdipoGen Life Sciences

Antibiotic. Antifungal and anti-yeast activity. Inhibits platelet aggregation induced by collagen or ADP. Has no effect on thrombin-induced platelet aggregation. Potent, cell permeable, reversible, ATP-competitive and broad spectrum inhibitor of protein kinases. Inhibits protein kinase A, CaM kinase, myosin light chain kinase, protein kinase C, protein kinase G, CDK1/cyclin B, CDK2/cyclin A, CDK4/cyclin D, CDK5/p25, […]

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Staurosporine 1 mg  | >98%

AdipoGen Life Sciences

Antibiotic. Antifungal and anti-yeast activity. Inhibits platelet aggregation induced by collagen or ADP. Has no effect on thrombin-induced platelet aggregation. Potent, cell permeable, reversible, ATP-competitive and broad spectrum inhibitor of protein kinases. Inhibits protein kinase A, CaM kinase, myosin light chain kinase, protein kinase C, protein kinase G, CDK1/cyclin B, CDK2/cyclin A, CDK4/cyclin D, CDK5/p25, […]

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Staurosporine 5 mg  | >98%

AdipoGen Life Sciences

Antibiotic. Antifungal and anti-yeast activity. Inhibits platelet aggregation induced by collagen or ADP. Has no effect on thrombin-induced platelet aggregation. Potent, cell permeable, reversible, ATP-competitive and broad spectrum inhibitor of protein kinases. Inhibits protein kinase A, CaM kinase, myosin light chain kinase, protein kinase C, protein kinase G, CDK1/cyclin B, CDK2/cyclin A, CDK4/cyclin D, CDK5/p25, […]

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Sterigmatocystin 1 mg  | >98%

AdipoGen Life Sciences

Intermediate of the biosynthetic pathway to aflatoxin B1. Mycotoxin. DNA synthesis inhibitor. Anticancer compound. Cytotoxic, carcinogenic and mutagenic. Acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitor. Shown to induce apoptosis in human peripheral lymphocytes and necrosis in rat liver. Induces sister chromatid exchanges in murine bone marrow cells.

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Sterigmatocystin 5 mg  | >98%

AdipoGen Life Sciences

Intermediate of the biosynthetic pathway to aflatoxin B1. Mycotoxin. DNA synthesis inhibitor. Anticancer compound. Cytotoxic, carcinogenic and mutagenic. Acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitor. Shown to induce apoptosis in human peripheral lymphocytes and necrosis in rat liver. Induces sister chromatid exchanges in murine bone marrow cells.

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Stevioside hydrate 10 mg  | >95%

AdipoGen Life Sciences

Noncaloric natural sweetener, 300 times more potent than sucrose. Antidiabetic. Antihyperglycaemic and antihypoglycaemic. Potentiates insulin secretion. Enhances acetyl-CoA carboxylase (ACC) gene expression. Increases insulin sensitivity.. Antihypertensive. Ca2+ influx inhibitor. Anticancer compound. Chemopreventive. Anti-inflammatory. IKKbeta, NF-kappaB and MAPK signaling inhibitor. Induces TNF-alpha, IL-1beta and nitric oxide release. Immunomodulator. Increasees phagocytic activity, haemagglutination antibody titre, delayed type […]

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Stevioside hydrate 50 mg  | >95%

AdipoGen Life Sciences

Noncaloric natural sweetener, 300 times more potent than sucrose. Antidiabetic. Antihyperglycaemic and antihypoglycaemic. Potentiates insulin secretion. Enhances acetyl-CoA carboxylase (ACC) gene expression. Increases insulin sensitivity.. Antihypertensive. Ca2+ influx inhibitor. Anticancer compound. Chemopreventive. Anti-inflammatory. IKKbeta, NF-kappaB and MAPK signaling inhibitor. Induces TNF-alpha, IL-1beta and nitric oxide release. Immunomodulator. Increasees phagocytic activity, haemagglutination antibody titre, delayed type […]

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Stigmasterol 1 g  | >95%

AdipoGen Life Sciences

Anti-hypercholestrolemic compound. Anti-inflammatory and immune-modulating effects. Anticancer compound. Chemopreventive. Cytostatic. Cell growth inhibitor. Antimutagenic. Potent in vitro antagonist of FXR (farnesoid X receptor). DNA polymerase beta inhibitor. Potent antioxidant, hypoglycemic and thyroid inhibiting agent. Anti-osteoarthritic. Decreases the expression of matrix metalloproteinases. Neuroprotective. Is used as a precursor for synthetic progesterone and vitamin D3 and is […]

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Stigmasterol 5 g  | >95%

AdipoGen Life Sciences

Anti-hypercholestrolemic compound. Anti-inflammatory and immune-modulating effects. Anticancer compound. Chemopreventive. Cytostatic. Cell growth inhibitor. Antimutagenic. Potent in vitro antagonist of FXR (farnesoid X receptor). DNA polymerase beta inhibitor. Potent antioxidant, hypoglycemic and thyroid inhibiting agent. Anti-osteoarthritic. Decreases the expression of matrix metalloproteinases. Neuroprotective. Is used as a precursor for synthetic progesterone and vitamin D3 and is […]

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Streptochlorin 250 µg  | >95%

AdipoGen Life Sciences

Antibiotic. TNF-alpha-induced NF-kappaB activation inhibitor. Antiangiogenic. Apoptosis inducer. Anticancer compound. Selective cytotoxic against several cancer cell lines. Tyrosinase inhibitor.

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Streptochlorin 1 mg  | >95%

AdipoGen Life Sciences

Antibiotic. TNF-alpha-induced NF-kappaB activation inhibitor. Antiangiogenic. Apoptosis inducer. Anticancer compound. Selective cytotoxic against several cancer cell lines. Tyrosinase inhibitor.

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Streptozotocin 50 mg  | >98%

AdipoGen Life Sciences

Antibiotic. Diabetogenic. Diabetes inducer. Induces diabetes mellitus in animal models through its toxic effects on pancreatic beta-cells. Mutagenic. Potent alkylating agent. Potent DNA methylating agent. Nitric oxide (NO) donor. Vasorelaxant. Cytotoxic to cells that express GLUT2 glucose transporter. O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase (O-GlcNAcase) inhibitor. Genotoxic. Induces DNA damage. Produces DNA strand breaks. Cell death inducer. Antineoplastic. Anti-cancer […]

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Streptozotocin 250 mg  | >98%

AdipoGen Life Sciences

Antibiotic. Diabetogenic. Diabetes inducer. Induces diabetes mellitus in animal models through its toxic effects on pancreatic beta-cells. Mutagenic. Potent alkylating agent. Potent DNA methylating agent. Nitric oxide (NO) donor. Vasorelaxant. Cytotoxic to cells that express GLUT2 glucose transporter. O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase (O-GlcNAcase) inhibitor. Genotoxic. Induces DNA damage. Produces DNA strand breaks. Cell death inducer. Antineoplastic. Anti-cancer […]

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Streptozotocin 1 g  | >98%

AdipoGen Life Sciences

Antibiotic. Diabetogenic. Diabetes inducer. Induces diabetes mellitus in animal models through its toxic effects on pancreatic beta-cells. Mutagenic. Potent alkylating agent. Potent DNA methylating agent. Nitric oxide (NO) donor. Vasorelaxant. Cytotoxic to cells that express GLUT2 glucose transporter. O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase (O-GlcNAcase) inhibitor. Genotoxic. Induces DNA damage. Produces DNA strand breaks. Cell death inducer. Antineoplastic. Anti-cancer […]

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Suc-Leu-Leu-Val-Tyr-AMC 1 mg  | >95%

AdipoGen Life Sciences

Fluorogenic substrate for measuring the chymotrypsin-like peptidase activity of the 20S proteasome, calpains and other chymotrypsin-like proteases. Extinction: 380nm. Emission: 460 nm. This substrate is useful for inhibitor screening and kinetic analysis.

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Suc-Leu-Leu-Val-Tyr-AMC 5 mg  | >95%

AdipoGen Life Sciences

Fluorogenic substrate for measuring the chymotrypsin-like peptidase activity of the 20S proteasome, calpains and other chymotrypsin-like proteases. Extinction: 380nm. Emission: 460 nm. This substrate is useful for inhibitor screening and kinetic analysis.

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Suc-Leu-Tyr-AMC 5 mg  | >98%

AdipoGen Life Sciences

Fluorogenic substrate for measuring the chymotrypsin-like peptidase activity of the 20S proteasome. Fluorogenic substrate for calpain and papain. Peptide substrate for Ti protease from E.coli. Excitation: 360nm. Emission: 460nm. This substrate is useful for inhibitor screening and kinetic analysis.

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Sulfamethoxazole hydroxylamine 10 mg  | >98%

AdipoGen Life Sciences

Metabolite of sulfamethoxazole, a sulfonamide bacteriostatic antibiotic. Has been shown to be an important component in sulfonamide hypersensitivity reactions and has been implicated in sulfonamide-mediated immunomodulatory effects. Shown to induce lymphocyte toxicity and suppression of proliferation. Compound can be used as analytical reference material.

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Sulfamethoxazole hydroxylamine 25 mg  | >98%

AdipoGen Life Sciences

Metabolite of sulfamethoxazole, a sulfonamide bacteriostatic antibiotic. Has been shown to be an important component in sulfonamide hypersensitivity reactions and has been implicated in sulfonamide-mediated immunomodulatory effects. Shown to induce lymphocyte toxicity and suppression of proliferation. Compound can be used as analytical reference material.

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Sulfluramid 100 mg  | >98%

AdipoGen Life Sciences

Perfluorinated delayed-action insecticide/pesticide. Mode of action is by uncoupling oxidative phosphorylation via disruption of the proton gradient. Suppresses immunoglobulin (Ig) M production in mice. Shown to be cytotoxic. Compound can be used as analytical reference material.

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Sulfluramid 250 mg  | >98%

AdipoGen Life Sciences

Perfluorinated delayed-action insecticide/pesticide. Mode of action is by uncoupling oxidative phosphorylation via disruption of the proton gradient. Suppresses immunoglobulin (Ig) M production in mice. Shown to be cytotoxic. Compound can be used as analytical reference material.

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Sulfluramid 500 mg  | >98%

AdipoGen Life Sciences

Perfluorinated delayed-action insecticide/pesticide. Mode of action is by uncoupling oxidative phosphorylation via disruption of the proton gradient. Suppresses immunoglobulin (Ig) M production in mice. Shown to be cytotoxic. Compound can be used as analytical reference material.

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