AdipoGen Life Sciences

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AdipoGen Life Sciences develops and manufactures new products for the Life Science Research Market in the key areas of cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cell biology, and neurodegeneration. The product portfolio consists of antibodies, proteins, ELISA Kits and innovative small molecules. The chemical portfolio includes, rare antibiotics, unique natural products, synthetic kinase modulators, fluorescent probes and much more.

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RO-3306 5 mg  | >95%

AdipoGen Life Sciences

Selective CDK 1 inhibitor (Cdk1/B1 and Cdk1/A). Potential anti-cancer compound. Cell cycle arrest inducer at G1, S and G2/M . Apoptosis inducer in embryonic stem cells. Actively enhances downstream p53 signaling to promote apoptosis in AML cell lines. Suppresses phosphorylation of p53 at Ser315 and procaspase-8 at Ser387. Enhances Fas-mediated activation and processing of procaspase-8 […]

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Robotnikinin 1 mg  | >97%

AdipoGen Life Sciences

Sonic hedgehog (Shh) signaling modulator. Inhibits the Shh pathway in human cell lines upstream of Smo. Targets the Shh N-terminal protein.

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Roquefortine C 500 µg  | >98%

AdipoGen Life Sciences

Potent neurotoxin. Mycotoxin. Tremorgenic. Gram-positive bacteria growth inhibitor. Cytochrome p450 inhibitor. Lymphocyte proliferation inhibitor. Cytotoxic.

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Roquefortine C 1 mg  | >98%

AdipoGen Life Sciences

Potent neurotoxin. Mycotoxin. Tremorgenic. Gram-positive bacteria growth inhibitor. Cytochrome p450 inhibitor. Lymphocyte proliferation inhibitor. Cytotoxic.

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Rosiglitazone 10 mg  | >98%

AdipoGen Life Sciences

Antidiabetic, hypoglycemic agent. Potent and selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist. Potent insulin sensitizing agent binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. Ameliorates insulin resistance. Improves blood pressure and vascular function. Enhances proliferation of endogenous neural progenitor cells (NPCs). Anti-inflammatory compound. Has controversial therapeutic effects […]

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Rosiglitazone 25 mg  | >98%

AdipoGen Life Sciences

Antidiabetic, hypoglycemic agent. Potent and selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist. Potent insulin sensitizing agent binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. Ameliorates insulin resistance. Improves blood pressure and vascular function. Enhances proliferation of endogenous neural progenitor cells (NPCs). Anti-inflammatory compound. Has controversial therapeutic effects […]

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Rosiglitazone 100 mg  | >98%

AdipoGen Life Sciences

Antidiabetic, hypoglycemic agent. Potent and selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist. Potent insulin sensitizing agent binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. Ameliorates insulin resistance. Improves blood pressure and vascular function. Enhances proliferation of endogenous neural progenitor cells (NPCs). Anti-inflammatory compound. Has controversial therapeutic effects […]

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Rosiglitazone 1 g  | >98%

AdipoGen Life Sciences

Antidiabetic, hypoglycemic agent. Potent and selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist. Potent insulin sensitizing agent binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. Ameliorates insulin resistance. Improves blood pressure and vascular function. Enhances proliferation of endogenous neural progenitor cells (NPCs). Anti-inflammatory compound. Has controversial therapeutic effects […]

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Rosiglitazone . maleate 25 mg  | >98%

AdipoGen Life Sciences

Same activities as rosaglitazone (Prod. No. AG-CR1-3570) but different formulation. Antidiabetic, hypoglycemic agent. Potent and selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist. Potent insulin sensitizing agent binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. Ameliorates insulin resistance. Improves blood pressure and vascular function. Enhances proliferation of endogenous […]

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Rosiglitazone . maleate 100 mg  | >98%

AdipoGen Life Sciences

Same activities as rosaglitazone (Prod. No. AG-CR1-3570) but different formulation. Antidiabetic, hypoglycemic agent. Potent and selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist. Potent insulin sensitizing agent binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. Ameliorates insulin resistance. Improves blood pressure and vascular function. Enhances proliferation of endogenous […]

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Rosiglitazone . maleate 1 g  | >98%

AdipoGen Life Sciences

Same activities as rosaglitazone (Prod. No. AG-CR1-3570) but different formulation. Antidiabetic, hypoglycemic agent. Potent and selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist. Potent insulin sensitizing agent binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. Ameliorates insulin resistance. Improves blood pressure and vascular function. Enhances proliferation of endogenous […]

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Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 1 mg  | >97%

AdipoGen Life Sciences

Activated ester of ruthenium complex for acylation of amino acid side chain amines. This label is perfectly suitable for 1D- or 2D-protein gel staining. A simple pre-electrophoresis procedure provides a sensitivity better than SYPRO Ruby and a similar dynamic range. In contrast to SYPRO Ruby, this staining exhibits a logarithmic dependency on the amount of […]

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Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 5 mg  | >97%

AdipoGen Life Sciences

Activated ester of ruthenium complex for acylation of amino acid side chain amines. This label is perfectly suitable for 1D- or 2D-protein gel staining. A simple pre-electrophoresis procedure provides a sensitivity better than SYPRO Ruby and a similar dynamic range. In contrast to SYPRO Ruby, this staining exhibits a logarithmic dependency on the amount of […]

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Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 100 mg  | >97%

AdipoGen Life Sciences

Activated ester of ruthenium complex for acylation of amino acid side chain amines. This label is perfectly suitable for 1D- or 2D-protein gel staining. A simple pre-electrophoresis procedure provides a sensitivity better than SYPRO Ruby and a similar dynamic range. In contrast to SYPRO Ruby, this staining exhibits a logarithmic dependency on the amount of […]

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Rubiginone A2 1 mg  | >98%

AdipoGen Life Sciences

Antibiotic. Antibacterial. Stereoisomer of SNA 8073B which is a prolyl endopeptidase (PEP) inhibitor. Vincristine-induced cytotoxicity potentiating activity against multi-drug-resistant tumor cells.

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Rubiginone A2 5 mg  | >98%

AdipoGen Life Sciences

Antibiotic. Antibacterial. Stereoisomer of SNA 8073B which is a prolyl endopeptidase (PEP) inhibitor. Vincristine-induced cytotoxicity potentiating activity against multi-drug-resistant tumor cells.

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Rubratoxin A 250 µg  | >95%

AdipoGen Life Sciences

Mycotoxin. Potent and selective competitive protein phosphatase 2A (PP2A) inhibitor. Does not inhibit PP1, PP2B, PTP1B, ALP and CIP. Antitumor agent. Antimetastatic.

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Rubratoxin A 500 µg  | >95%

AdipoGen Life Sciences

Mycotoxin. Potent and selective competitive protein phosphatase 2A (PP2A) inhibitor. Does not inhibit PP1, PP2B, PTP1B, ALP and CIP. Antitumor agent. Antimetastatic.

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Rubrofusarin 1 mg  | >98%

AdipoGen Life Sciences

Monomer of aurofusarin. Mycotoxin. Anticancer and antimycobacterial compound in vivo. Moderate tyrosinase inhibitor. Anti-estrogenic.

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Rubrofusarin 5 mg  | >98%

AdipoGen Life Sciences

Monomer of aurofusarin. Mycotoxin. Anticancer and antimycobacterial compound in vivo. Moderate tyrosinase inhibitor. Anti-estrogenic.

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Rugulosin 250 µg  | >95%

AdipoGen Life Sciences

Antibiotic. Antibacteriophage. Antiviral. Mycotoxin. DNA replication, transcription and repair inhibitor. Antibacterial. RNA polymerase and ribonuclease H inhibitor. Insecticidal. Cytotoxic. HIV-1 integrase inhibitor. Shows anti-MRSA (methicillin-resistant Staphylococcus aureus) activity. Potential Hsp90 inhibitor through interacting with N-Hsp90.

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Rugulosin 1 mg  | >95%

AdipoGen Life Sciences

Antibiotic. Antibacteriophage. Antiviral. Mycotoxin. DNA replication, transcription and repair inhibitor. Antibacterial. RNA polymerase and ribonuclease H inhibitor. Insecticidal. Cytotoxic. HIV-1 integrase inhibitor. Shows anti-MRSA (methicillin-resistant Staphylococcus aureus) activity. Potential Hsp90 inhibitor through interacting with N-Hsp90.

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Rugulosin [(+]-Rugulosin] 5 mg  | >98%

AdipoGen Life Sciences

Mycotoxin. Antibiotic (Streptococcus, Corynebacterium, MRSA). Antiviral, HIV-1 integrase inhibitor. DNA replication, transcription and repair inhibitor (carcinogenic activity). RNA polymerase and ribonuclease H inhibitor. Insecticidal activity. Inhibitor of N-Hsp90.

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Rutin . trihydrate 5 g  | >95%

AdipoGen Life Sciences

Antioxidant. Free radical scavenger. Nitric oxide (NO) scavenger. Anticancer compound. Antiproliferative. Apoptosis inducer. Reduces induced DNA damage. Protective against carcinogenesis. Hypolipidaemic. Reduces triacylglycerol levels. Anti-inflammatory. Platelet aggregation inhibitor. Anti-hyperglycaemic. Anti-adipogenic. Insulin-mimetic. Activates synthesis of glucose transporter GLUT4. Neuroprotective. Cardioprotective. Reduces lipid peroxidation. Weak alpha-glucosidase inhibitor. Vasodilatory compound.

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Ruxolitinib . phosphate salt 5 mg  | >97%

AdipoGen Life Sciences

Water-soluble phosphate salt of Ruxolitinib. Antineoplastic, anti-inflammatory and immunomodulating agent. Orally bioavailable potent ATP mimetic that inhibits both JAK1 and JAK2 with IC50 values of 2.7 and 4.5nM, respectively and is less selective for JAK3 (IC50=322nM). Affects DC differentiation and function, leading to impaired T cell activation. Used in the treatment of myeloproliferative neoplasms and […]

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Ruxolitinib . phosphate salt 25 mg  | >97%

AdipoGen Life Sciences

Water-soluble phosphate salt of Ruxolitinib. Antineoplastic, anti-inflammatory and immunomodulating agent. Orally bioavailable potent ATP mimetic that inhibits both JAK1 and JAK2 with IC50 values of 2.7 and 4.5nM, respectively and is less selective for JAK3 (IC50=322nM). Affects DC differentiation and function, leading to impaired T cell activation. Used in the treatment of myeloproliferative neoplasms and […]

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Ruxolitinib (free base) 5 mg  | >98%

AdipoGen Life Sciences

Antineoplastic, anti-inflammatory and immunomodulating agent. Orally bioavailable potent ATP mimetic that inhibits both JAK1 and JAK2 with IC50 values of 2.7 and 4.5nM, respectively and is less selective for JAK3 (IC50=322nM). Affects DC differentiation and function, leading to impaired T cell activation. Used in the treatment of myeloproliferative neoplasms and psoriasis. Anticancer agent. Shown to […]

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Ruxolitinib (free base) 25 mg  | >98%

AdipoGen Life Sciences

Antineoplastic, anti-inflammatory and immunomodulating agent. Orally bioavailable potent ATP mimetic that inhibits both JAK1 and JAK2 with IC50 values of 2.7 and 4.5nM, respectively and is less selective for JAK3 (IC50=322nM). Affects DC differentiation and function, leading to impaired T cell activation. Used in the treatment of myeloproliferative neoplasms and psoriasis. Anticancer agent. Shown to […]

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S-(5′)-Adenosyl-3-thiopropylamine 10 mg  | >98%

AdipoGen Life Sciences

This decarboxylated S-Adenosyl-L-methionine is an important metabolite in polyamine biosynthesis, acting as aminopropyl group donor for propylamine transferases such as spermine synthase and spermidine synthase.

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S-(5′)-Adenosyl-3-thiopropylamine 50 mg  | >98%

AdipoGen Life Sciences

This decarboxylated S-Adenosyl-L-methionine is an important metabolite in polyamine biosynthesis, acting as aminopropyl group donor for propylamine transferases such as spermine synthase and spermidine synthase.

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S-BAIBA 100 mg  | >99%

AdipoGen Life Sciences

Beta-Aminoisobutyric acid is a non-protein amino acid originating from the catabolism of thymine and valine. beta-Aminoisobutyric acid occurs in two isomeric forms and both enantiomers of beta-Aminoisobutyric acid can be detected in human urine and plasma. In plasma, the S-enantiomer is the predominant type due to active renal reabsorption. In contrast, urine almost exclusively contains […]

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S-BAIBA 500 mg  | >99%

AdipoGen Life Sciences

Beta-Aminoisobutyric acid is a non-protein amino acid originating from the catabolism of thymine and valine. beta-Aminoisobutyric acid occurs in two isomeric forms and both enantiomers of beta-Aminoisobutyric acid can be detected in human urine and plasma. In plasma, the S-enantiomer is the predominant type due to active renal reabsorption. In contrast, urine almost exclusively contains […]

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S14161 1 mg  | >99%

AdipoGen Life Sciences

Potent antileukemia and antimyeloma compound. Apoptosis inducer. Delays tumor growth. Cyclin D2 promoter transactivation inhibitor. Inhibitor of pan-Class I PI3K isoforms.

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S14161 5 mg  | >99%

AdipoGen Life Sciences

Potent antileukemia and antimyeloma compound. Apoptosis inducer. Delays tumor growth. Cyclin D2 promoter transactivation inhibitor. Inhibitor of pan-Class I PI3K isoforms.

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SAG 1 mg  | >98%

AdipoGen Life Sciences

Cell permeable Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Induces Sonic hedgehog (Shh) pathway activation and counteracts cyclopamine inhibition of Smo. Acts as an activator of Smo at low concentrations and as an inhibitor of Smo at very high concentrations. Potent activator of VEGF expression in vitro.

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SAG 5 mg  | >98%

AdipoGen Life Sciences

Cell permeable Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Induces Sonic hedgehog (Shh) pathway activation and counteracts cyclopamine inhibition of Smo. Acts as an activator of Smo at low concentrations and as an inhibitor of Smo at very high concentrations. Potent activator of VEGF expression in vitro.

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SAG . dihydrochloride (water soluble) 1 mg  | >98%

AdipoGen Life Sciences

Cell permeable Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Induces Sonic hedgehog (Shh) pathway activation and counteracts cyclopamine inhibition of Smo. Acts as an activator of Smo at low concentrations and as an inhibitor of Smo at very high concentrations. Potent activator of VEGF expression in vitro.

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SAG . dihydrochloride (water soluble) 5 mg  | >98%

AdipoGen Life Sciences

Cell permeable Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Induces Sonic hedgehog (Shh) pathway activation and counteracts cyclopamine inhibition of Smo. Acts as an activator of Smo at low concentrations and as an inhibitor of Smo at very high concentrations. Potent activator of VEGF expression in vitro.

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SAG Analog (LowTox) 1 mg  | >98%

AdipoGen Life Sciences

Cell permeable low toxicity Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Potent activator of VEGF expression in vitro.

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Salidroside 25 mg  | >98%

AdipoGen Life Sciences

Glycoside isolated from plants, most commonly from members of the genus Rhodiola, with many biological activities. Shown to have neuroprotective, antioxidant, antiviral, antidepressant, cardioprotective, anti-inflammatory and anticancer activity. Ameliorates insulin resistance.

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Salidroside 100 mg  | >98%

AdipoGen Life Sciences

Glycoside isolated from plants, most commonly from members of the genus Rhodiola, with many biological activities. Shown to have neuroprotective, antioxidant, antiviral, antidepressant, cardioprotective, anti-inflammatory and anticancer activity. Ameliorates insulin resistance.

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Salidroside 500 mg  | >98%

AdipoGen Life Sciences

Glycoside isolated from plants, most commonly from members of the genus Rhodiola, with many biological activities. Shown to have neuroprotective, antioxidant, antiviral, antidepressant, cardioprotective, anti-inflammatory and anticancer activity. Ameliorates insulin resistance.

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Salinosporamide A 100 µg  | >95%

AdipoGen Life Sciences

Potent, irreversible inhibitor of all the 3 proteolytic activities of the mammalian 20S proteasome. beta5 subunit: chymotrypsin-like (EC50 = 3.5nM) beta2 subunit: trypsin-like (EC50 = 28nM) beta1 subunit: caspase-like or peptidyl-glutamyl peptide-hydrolyzing (PGPH) (EC50 = 430nM) Potent anticancer compound. Triggers apoptosis, with distinct proteasome activity and mechanism of action compared to bortezomib (Velcade) (Prod. No. […]

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Salsalate 1 g  | >98%

AdipoGen Life Sciences

Nonacetylated salicylate. Non-steroidal anti-inflammatory drug (NSAID). Reduces pain and inflammation caused by conditions such as rheumatoid arthritis, osteoarthritis and related rheumatic conditions. Prostaglandin synthesis inhibitor in vivo. Inactivates cyclooxygenase-1 (COX-1) and -2 (COX-2). IKKbeta/NF-kappaB inhibitor (at significantly higher concentrations than required for COX inhibition). Used to target inflammation in the treatment of insulin resistance, type […]

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Salsalate 5 g  | >98%

AdipoGen Life Sciences

Nonacetylated salicylate. Non-steroidal anti-inflammatory drug (NSAID). Reduces pain and inflammation caused by conditions such as rheumatoid arthritis, osteoarthritis and related rheumatic conditions. Prostaglandin synthesis inhibitor in vivo. Inactivates cyclooxygenase-1 (COX-1) and -2 (COX-2). IKKbeta/NF-kappaB inhibitor (at significantly higher concentrations than required for COX inhibition). Used to target inflammation in the treatment of insulin resistance, type […]

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