Benzimidazole is a heterocyclic aromatic organic compound. This bicyclic compound consists of the fusion of benzene and imidazole. The most prominent benzimidazole compound in nature is N-ribosyl-dimethylbenzimidazole, which serves as an axial ligand for cobalt in vitamin B12. Benzimidazole, in an extension of the well-elaborated imidazole system, has been used as carbon skeletons for N-heterocyclic […]

Benzimidazole is a heterocyclic aromatic organic compound. This bicyclic compound consists of the fusion of benzene and imidazole. The most prominent benzimidazole compound in nature is N-ribosyl-dimethylbenzimidazole, which serves as an axial ligand for cobalt in vitamin B12. Benzimidazole, in an extension of the well-elaborated imidazole system, has been used as carbon skeletons for N-heterocyclic […]

Desipramine is a drug belonging to the tricyclic antidepressant (TCA) class, whose action is to inhibit the reuptake of norepinephrine. In addition to the treatment of depression, Desipramine has also found use in treating neuropathic pain and the symptoms of Attention Deficit Disorder (which has been linked to the underproduction of norepinephrine).

Benzoylecgonine is the predominantcocaine metabolite. This compound is not biologically active but is used asan indicator of cocaine use.

Diclazuril (trade name Vecoxan) is a coccidiostat.

Nicarbazin is an anticoccidial for the prevention of coccidiosis in broiler chickens.

Androstanediones are a pair of isomeric steroids which differ at the 5-position. They are distinguished as 5α-androstanedione and 5β-androstanedione. In humans, 5α-androstanedione is a metabolic precursor of both testosterone and estrone.

Norfluoxetine is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Fluoxetine is approved for the treatment of major depression (including pediatric depression), obsessive-compulsive disorder (in both adult and pediatric populations), bulimia nervosa, panic disorder and premenstrual dysphoric disorder. Fluoxetine is metabolized in the liver by isoenzymes of the cytochrome P450 system, including CyP2D6.

Nordazepam (marketed under brand names Nordaz, Stilny, Madar, Vegesan, and Calmday), also known as desoxydemoxepam, nordiazepam and desmethyldiazepam, is a 1,4-benzodiazepine derivative. Like other benzodiazepine derivatives, it has anticonvulsant, anxiolytic, muscle relaxant and sedative properties. However, it is used primarily in the treatment of anxiety. It is an active metabolite of diazepam, chlordiazepoxide, clorazepate, prazepam, […]

Clinically, buprenorphine is utilized as a substitution therapy for opioid dependance and as an analgesic. Buprenorphine is a partial agonist of the mu-opioid receptor. These mu binding sites are discretely distributed in the human brain, spinal cord, and other tissue. The clinical effects of mu receptor agonists are sedation, euphoria, respiratory depression, and and analgesia.