The agents of Marijuana that cause various biological effects in humans are called cannabinoid. Cannabinoid is a central nervous stimulant that alters mood and sensory perceptions, produces loss of coordination, impairs short term memory, produces symptoms of anxiety, paranoia, depression, confusion, hallucination, and increased heart rate. Large doses of cannabinoid could cause the development of […]

Cortisol is the most potent glucocorticoid produced by the human adrenal. It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH) which is regulated by corticotropin releasing factor (CRF). ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop. In plasma a majority of cortisol […]

Digoxin is a beta blocker drug originally derived from the foxglove plant, Digitalis lanata. Digoxin is used primarily to improve the pumping ability of the heart in congestive heart failure (CHF), and treat problems such as high blood pressure. It is also used to help normalize some dysrhythmias (abnormal types of heartbeat).

γ-Hydroxybutyric acid (GHB), also known as 4-hydroxybutanoic acid and sodium oxybate (INN), is a naturally occurring substance found in the human central nervous system, as well as in wine, beef, small citrus fruits, and almost all animals in small amounts. It is also categorized as an illegal drug in many countries. It is currently regulated […]

Dapsone is a synthetic derivative of diamino-sulfone with anti-inflammatory and anti-bacterial properties. As a structural analog of?p-aminobenzoic acid?(PABA), dapsone inhibits?dihydropteroate?synthase (DHPS), an enzyme important in?folate?synthesis, resulting in a depletion of the?folate?pool and a reduction in the amount of?thymidylate?available for DNA synthesis. Although the exact mechanism through which dapsone exerts its anti-inflammatory activity has yet to […]

Phencyclidine, alsoknown as angel dust and myriad other street names, is a recreational,dissociative drug formerly used as an anesthetic agent, exhibitinghallucinogenic and neurotoxic effects. Developed in Germany in 1926, it wasfirst patented in 1952 by the Parke-Davis pharmaceutical company and marketedunder the brand name Sernyl. In chemical structure, PCP is anarylcyclohexylamine derivative, and, in pharmacology, […]

Oxycodone is a semi-synthetic opioid synthesized from poppy-derived thebaine. It is a narcotic analgesic generally indicated for relief of moderate to severe pain. It was developed in 1916 in Germany as one of several new semi-synthetic opioids in an attempt to improve on the existing opioids.