MedChem Express

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MedChemExpress has an experienced team of custom synthesis chemists, led by an impressive group of Ph.D.'s. With this team, we have the capability of supporting all kinds of chemistry projects of multiple step syntheses of complex labeled molecules, including metabolites and steroids. Following scientific and technological innovation, challenging traditional thinking, MedChemExpress has always been committed to develop quality products that exceed international standards on cost and reliability, to create the most advanced synthetic route. With high experiences in preparing a large numbers of different biologically active molecules, we provide rapid synthesis of new products. That is why we can consistently deliver your custom synthesis compounds faster than any other company.

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Me-Tet-PEG4-NHS | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Me-Tet-PEG4-NHS is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

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Me-Tet-PEG5-COOH | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Me-Tet-PEG5-COOH is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

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Me-Tet-PEG5-NHS | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Me-Tet-PEG5-NHS is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

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Me-Tet-PEG8-Maleimide | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Me-Tet-PEG8-Maleimide is an ADC Linker containing 8 PEG units. Me-Tet-PEG8-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.

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Me-Tet-PEG8-NH2 hydrochloride | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Me-Tet-PEG8-NH2 (hydrochloride) is an ADC Linker containing 2 PEG units. Me-Tet-PEG8-NH2 (hydrochloride) can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

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Me-Tet-PEG8-NHBoc | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Me-Tet-PEG8-NHBoc is an ADC Linker containing 8 PEG units. Me-Tet-PEG8-NHBoc can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

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Me-Tet-PEG9-COOH | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Me-Tet-PEG9-COOH is an ADC Linker containing 9 PEG units. Me-Tet-PEG9-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

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Me-Tet-PEG9-NHS | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Me-Tet-PEG9-NHS is an ADC Linker containing 9 PEG units. Me-Tet-PEG9-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

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Me4Phen | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Me4Phen (compound 3) is an oxygen rhenium (V) complex that depletes mitochondrial membrane potential and upregulates intracellular reactive oxygen species (ROS), leading to endoplasmic reticulum stress-mediated necrosis of cancer cells. Me4Phen is highly lipophilic and effectively overcomes Cisplatin (HY-17394) resistance in a variety of cancer cells[1].

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Mecbotamab | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Mecbotamab is a humanized IgG1-κ antibody targeting to AXL receptor tyrosine kinase (AXL). Mecbotamab can serves as a conditionally active biologic (CAB), which can be conjugated with MMAE (HY-15162) via a cleavable linker, to form ADC Mecbotamab vedotin (BA3011)[1][2].

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Medical fluorophore 33 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Medical fluorophore 33 is a novel quinoline-isoquinoline salt. Medical fluorophore 33 exhibits a strong fluorescent signal, good microsomal stability and high biocompatibility in vivo. Medical fluorophore 33 has antitumor activity in colorectal cancer mice[1].

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Medroxyprogesterone acetate (Standard) | MedChemExpress (MCE) 25 mg  | 99.24%

MedChem Express

Medroxyprogesterone acetate (Standard) is the analytical standard of Medroxyprogesterone acetate. This product is intended for research and analytical applications. Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors[1].

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Medroxyprogesterone acetate (Standard) | MedChemExpress (MCE) 50 mg  | 99.24%

MedChem Express

Medroxyprogesterone acetate (Standard) is the analytical standard of Medroxyprogesterone acetate. This product is intended for research and analytical applications. Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors[1].

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Medroxyprogesterone acetate (Standard) | MedChemExpress (MCE) 100 mg  | 99.24%

MedChem Express

Medroxyprogesterone acetate (Standard) is the analytical standard of Medroxyprogesterone acetate. This product is intended for research and analytical applications. Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors[1].

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MEDS433 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

MEDS433 is a potent inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC50 of 1.2 nM. MEDS433 exerts a potent antiviral activity against RSV-A and RSV-B in the one-digit nanomolar range. MEDS433 induces the expression of antiviral proteins encoded by interferon stimulated genes (ISGs) able to reduce RSV replication[1].

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MEGA-8 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

MEGA-8 (N-Octanoyl-N-methylglucamine) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

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MEGA-9 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

MEGA-9 (N-Nonanoyl-N-methylglucamine) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

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MegaUni 10M Virtual Diversity Library | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

With MCE’s 40,662 BBs, covering around 273 reaction types, more than 40 million molecules were generated. Compounds which comply with Ro5 criteria were selected. Inappropriate chemical structures, such as PAINS motifs and synthetically difficult accessible, were removed. Based on Morgan Fingerprint, molecular clustering analysis was carried out, and molecules close to each clustering center were […]

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MegaUni 50K Virtual Diversity Library | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

MegaUni 50K Virtual Diversity Library consists of 50,000 novel, synthetically accessible, lead-like compounds. With MCE’s 40,662 Building Blocks, covering around 273 reaction types, more than 40 million molecules were generated. Based on Morgan Fingerprint and Tanimoto Coefficient, molecular clustering analysis was carried out, and molecules closest to each clustering center were extracted to form a […]

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Megestrol acetate (Standard) | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Megestrol acetate (Standard) is the analytical standard of Megestrol acetate. This product is intended for research and analytical applications. Megestrol acetate is a synthetic and orally active progesteronal agent. Megestrol acetate is effective as an appetite stimulant for wasting syndromes such as cachexia. Megestrol acetate decreases nuclear and cytosol androgen receptors human BPH tissue. Megestrol […]

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Meglutol-d3 | MedChemExpress (MCE) 5 mg  | ≥98.00%

MedChem Express

Meglutol-d3 is the deuterium labeled Meglutol[1]. Meglutol is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids, and inhibits the activity of hydroxymethylglutarryl CoA reductases, which is the rate limiting enzyme in the biosynthesis of cholesterol.

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