MEDS433 | MedChemExpress (MCE)

MEDS433 is a potent inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC50 of 1.2 nM. MEDS433 exerts a potent antiviral activity against RSV-A and RSV-B in the one-digit nanomolar range. MEDS433 induces the expression of antiviral proteins encoded by interferon stimulated genes (ISGs) able to reduce RSV replication[1].

Trivial name MEDS433
Catalog Number HY-156442
Research Area Infection
CAS# 2241027-61-0
Purity ≥98.00%
SMILES O=C(C1=C2C=CC=CN2N=C1O)NC3=C(F)C(F)=C(C4=CC=CC=C4)C(F)=C3F
PubChem Chemical Structure ID 134686803
Size 1 mg
Supplier Page https://www.medchemexpress.com/meds433.html