AdipoGen Life Sciences

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AdipoGen Life Sciences develops and manufactures new products for the Life Science Research Market in the key areas of cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cell biology, and neurodegeneration. The product portfolio consists of antibodies, proteins, ELISA Kits and innovative small molecules. The chemical portfolio includes, rare antibiotics, unique natural products, synthetic kinase modulators, fluorescent probes and much more.

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2,4,5-Trichlorophenol 25 g  | >95%

AdipoGen Life Sciences

Building block for synthesis of pesticides. Used as a broad range pesticide against insects, fungi, vegetation and bacteria. It has become a common environmental contaminant and probable human carcinogen. Compound can be used as analytical reference material.

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2,4,5-Trichlorophenol 100 g  | >95%

AdipoGen Life Sciences

Building block for synthesis of pesticides. Used as a broad range pesticide against insects, fungi, vegetation and bacteria. It has become a common environmental contaminant and probable human carcinogen. Compound can be used as analytical reference material.

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2,5-Dimethyl-celecoxib 5 mg  | >99%

AdipoGen Life Sciences

Close structural analog of the selective cyclooxygenase-2 (COX-2) inhibitor celecoxib, that lacks COX-2 inhibitory function. Anti-proliferative, anti-tumorigenic and anti-angiogenic. Potent apoptosis inducer in many cancer cell lines. Down-regulates the expression of survivin, cyclins, MMPs and inhibits cyclin-dependent kinase activity. Modulates PDK-1, AKT, GSK3beta, p70 S6K, PKA and MAPKAP-K1alpha. Reduces phosphorylation of ERK1/2 but not AKT […]

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2,5-Dimethyl-celecoxib 25 mg  | >99%

AdipoGen Life Sciences

Close structural analog of the selective cyclooxygenase-2 (COX-2) inhibitor celecoxib, that lacks COX-2 inhibitory function. Anti-proliferative, anti-tumorigenic and anti-angiogenic. Potent apoptosis inducer in many cancer cell lines. Down-regulates the expression of survivin, cyclins, MMPs and inhibits cyclin-dependent kinase activity. Modulates PDK-1, AKT, GSK3beta, p70 S6K, PKA and MAPKAP-K1alpha. Reduces phosphorylation of ERK1/2 but not AKT […]

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2′,7′-Dichlorofluorescein 10 g  | >90%

AdipoGen Life Sciences

Fluorescent dye. Spectral data: Extinction 504nm/Emmission 529nm, in 0.1 M Tris pH 8.0. Used for the determination of carbohydrates by fluorescence densitometry after TLC, in the determination of H2O2 by chemiluminescence, and as a fluorescent additive used in indirect fluorimetric detection in OTC-HPLC. Used as a component/substrate of the 2′,7′-dichlorofluorescein diacetate (DCFH-DA) assay to quantitate […]

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2′,7′-Dichlorofluorescein 25 g  | >90%

AdipoGen Life Sciences

Fluorescent dye. Spectral data: Extinction 504nm/Emmission 529nm, in 0.1 M Tris pH 8.0. Used for the determination of carbohydrates by fluorescence densitometry after TLC, in the determination of H2O2 by chemiluminescence, and as a fluorescent additive used in indirect fluorimetric detection in OTC-HPLC. Used as a component/substrate of the 2′,7′-dichlorofluorescein diacetate (DCFH-DA) assay to quantitate […]

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2′,7′-Dichlorofluorescein 100 g  | >90%

AdipoGen Life Sciences

Fluorescent dye. Spectral data: Extinction 504nm/Emmission 529nm, in 0.1 M Tris pH 8.0. Used for the determination of carbohydrates by fluorescence densitometry after TLC, in the determination of H2O2 by chemiluminescence, and as a fluorescent additive used in indirect fluorimetric detection in OTC-HPLC. Used as a component/substrate of the 2′,7′-dichlorofluorescein diacetate (DCFH-DA) assay to quantitate […]

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2′-(4-Methylumbelliferyl)-alpha-D-N-acetylneuraminic acid sodium salt hydrate 1 mg  | >95%

AdipoGen Life Sciences

Fluorogenic substrate used to measure sensitively enzymatic neuraminidase activity in fluorometric assays in mammalian and viral sources. Neuraminidase is catalyzed by the hydrolysation to form N-acetylneuraminic acid and the blue fluorescent soluble compound 4-Methylumbelliferone, which can be detected fluorometrically. Spectral data: lambdaex 315 nm| lambdaem 374 nm (pH.7.0) or lambdaex 365 nm| lambdaem 445 nm […]

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2′-(4-Methylumbelliferyl)-alpha-D-N-acetylneuraminic acid sodium salt hydrate 5 mg  | >95%

AdipoGen Life Sciences

Fluorogenic substrate used to measure sensitively enzymatic neuraminidase activity in fluorometric assays in mammalian and viral sources. Neuraminidase is catalyzed by the hydrolysation to form N-acetylneuraminic acid and the blue fluorescent soluble compound 4-Methylumbelliferone, which can be detected fluorometrically. Spectral data: lambdaex 315 nm| lambdaem 374 nm (pH.7.0) or lambdaex 365 nm| lambdaem 445 nm […]

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2′-(4-Methylumbelliferyl)-alpha-D-N-acetylneuraminic acid sodium salt hydrate 25 mg  | >95%

AdipoGen Life Sciences

Fluorogenic substrate used to measure sensitively enzymatic neuraminidase activity in fluorometric assays in mammalian and viral sources. Neuraminidase is catalyzed by the hydrolysation to form N-acetylneuraminic acid and the blue fluorescent soluble compound 4-Methylumbelliferone, which can be detected fluorometrically. Spectral data: lambdaex 315 nm| lambdaem 374 nm (pH.7.0) or lambdaex 365 nm| lambdaem 445 nm […]

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20-Hydroxyecdysone 5 mg  | >95%

AdipoGen Life Sciences

A member of the ecdysteroid family. Ecdysone receptor (EcR) agonist. More potent than ecdysone. Induces the expression of genes coding for proteins that the larva requires, and it causes chromosome puffs (sites of high expression) to form in polytene chromosomes. Plays a key role in insect development, cell proliferaton, growth and apoptosis by controlling gene […]

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20-Hydroxyecdysone 10 mg  | >95%

AdipoGen Life Sciences

A member of the ecdysteroid family. Ecdysone receptor (EcR) agonist. More potent than ecdysone. Induces the expression of genes coding for proteins that the larva requires, and it causes chromosome puffs (sites of high expression) to form in polytene chromosomes. Plays a key role in insect development, cell proliferaton, growth and apoptosis by controlling gene […]

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20-Hydroxyecdysone 50 mg  | >95%

AdipoGen Life Sciences

A member of the ecdysteroid family. Ecdysone receptor (EcR) agonist. More potent than ecdysone. Induces the expression of genes coding for proteins that the larva requires, and it causes chromosome puffs (sites of high expression) to form in polytene chromosomes. Plays a key role in insect development, cell proliferaton, growth and apoptosis by controlling gene […]

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22-NHC . hydrochloride 1 mg  | >98%

AdipoGen Life Sciences

Aza-steroid. Hedgehog signaling inhibitor. Competes with 20(S)-OHC for access to the cysteine-rich domain in Smoothened (Smo). For control compound see 22-NHC (inactive isomer) (Prod. No. AG-CR1-3524) http://www.adipogen.com/ag-cr1-3524/22-nhc-inactive-isomer.html .

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22-NHC . hydrochloride 5 mg  | >98%

AdipoGen Life Sciences

Aza-steroid. Hedgehog signaling inhibitor. Competes with 20(S)-OHC for access to the cysteine-rich domain in Smoothened (Smo). For control compound see 22-NHC (inactive isomer) (Prod. No. AG-CR1-3524) http://www.adipogen.com/ag-cr1-3524/22-nhc-inactive-isomer.html .

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22-NHC (inactive isomer) 1 mg  | >98%

AdipoGen Life Sciences

Inactive control compound for hedgehog signaling inhibitor 22-NHC . HCl (Prod. No. AG-CR1-3523) http://www.adipogen.com/ag-cr1-3523/22-nhc-hydrochloride.html .

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22-NHC (inactive isomer) 5 mg  | >98%

AdipoGen Life Sciences

Inactive control compound for hedgehog signaling inhibitor 22-NHC . HCl (Prod. No. AG-CR1-3523) http://www.adipogen.com/ag-cr1-3523/22-nhc-hydrochloride.html .

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3-(2-Furoyl)quinoline-2-carboxaldehyde 10 mg  | >95%

AdipoGen Life Sciences

3-(2-Furoyl)quinoline-2-carboxaldehyde (FQCA) is a fluorogenic derivatizing reagent for liquid chromatography suitable for high-sensitivity analysis of amino acids by laser-induced fluorescence with an argon-ion laser. The reagent forms highly fluorescent isoindoles upon reaction with primary amines. It is used for the determination of isoelectronic points (pI values) of proteins with laser-induced fluorescence detection (c-IEF-LIF). C-IEF-LIF technique […]

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3-(2-Furoyl)quinoline-2-carboxaldehyde 50 mg  | >95%

AdipoGen Life Sciences

3-(2-Furoyl)quinoline-2-carboxaldehyde (FQCA) is a fluorogenic derivatizing reagent for liquid chromatography suitable for high-sensitivity analysis of amino acids by laser-induced fluorescence with an argon-ion laser. The reagent forms highly fluorescent isoindoles upon reaction with primary amines. It is used for the determination of isoelectronic points (pI values) of proteins with laser-induced fluorescence detection (c-IEF-LIF). C-IEF-LIF technique […]

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3-(4-tert.-Butyl-1-pyridinio)-1-propanesulfonate 1 g  | >98%

AdipoGen Life Sciences

NDSB-256-4T is a non-detergent sulfobetaine (NDSB) that prevents protein aggregation and facilitates protein-folding, presumably by interacting with the early folding intermediates. Shown to improve the in vitro renaturation efficiency of reduced hen lysozyme and chemically unfolded tryptophan synthase beta2 subunit.

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3-(4-tert.-Butyl-1-pyridinio)-1-propanesulfonate 3 g  | >98%

AdipoGen Life Sciences

NDSB-256-4T is a non-detergent sulfobetaine (NDSB) that prevents protein aggregation and facilitates protein-folding, presumably by interacting with the early folding intermediates. Shown to improve the in vitro renaturation efficiency of reduced hen lysozyme and chemically unfolded tryptophan synthase beta2 subunit.

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3-Aminoisobutyric acid [BAIBA] 250 mg  | >98%

AdipoGen Life Sciences

Catabolite of thymine. Precursor for 3-Hydroxyisobutyric acid synthesis. Small molecule myokine. Browning inducer of white adipose tissue (WAT) into brown adipose tissue (BAT). PGC-1alpha-mediated and exercise-triggered nonadrenergic activator of the thermogenic program in WAT. Increases the expression of brown adipocyte-specific genes (browning) in white adipocytes and beta-oxidation in hepatocytes through a PPARalpha-mediated mechanism. Induces a […]

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3-Aminoisobutyric acid [BAIBA] 1 g  | >98%

AdipoGen Life Sciences

Catabolite of thymine. Precursor for 3-Hydroxyisobutyric acid synthesis. Small molecule myokine. Browning inducer of white adipose tissue (WAT) into brown adipose tissue (BAT). PGC-1alpha-mediated and exercise-triggered nonadrenergic activator of the thermogenic program in WAT. Increases the expression of brown adipocyte-specific genes (browning) in white adipocytes and beta-oxidation in hepatocytes through a PPARalpha-mediated mechanism. Induces a […]

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3-Carboxy-6,8-difluoro-7-hydroxycoumarin 25 mg  | >98%

AdipoGen Life Sciences

This amine-reactive reagent can be used to create blue-fluorescent bioconjugates with excitation/emission maxima ~410/455 nm that are excitable by the 405 nm spectral line of the blue diode (violet) laser. Used in highly sensitive analyses of amines, amino acids and dipeptides. Amine-reactive reagents react with non-protonated aliphatic amine groups, including the amine terminus of proteins […]

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3-Carboxy-6,8-difluoro-7-hydroxycoumarin 100 mg  | >98%

AdipoGen Life Sciences

This amine-reactive reagent can be used to create blue-fluorescent bioconjugates with excitation/emission maxima ~410/455 nm that are excitable by the 405 nm spectral line of the blue diode (violet) laser. Used in highly sensitive analyses of amines, amino acids and dipeptides. Amine-reactive reagents react with non-protonated aliphatic amine groups, including the amine terminus of proteins […]

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3-cis-Hydroxyglibenclamide 1 mg  | >97%

AdipoGen Life Sciences

M2-Metabolite of the antidiabetic compound glyburide. Antidiabetic reagent. Shows 50% hypoglycaemic activity of the parent compound, by increasing insulin secretion. Compound can be used as analytical reference material.

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3-cis-Hydroxyglibenclamide 5 mg  | >97%

AdipoGen Life Sciences

M2-Metabolite of the antidiabetic compound glyburide. Antidiabetic reagent. Shows 50% hypoglycaemic activity of the parent compound, by increasing insulin secretion. Compound can be used as analytical reference material.

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3-Cyano-7-ethoxycoumarin 20 mg  | >99%

AdipoGen Life Sciences

Substrate for determination of cytochrom P-450 dependent oxidases; about 50-100 times more sensitive than conventional substrate ethoxy-resorufin due to higher turn over rate.

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3-Cyano-7-ethoxycoumarin 100 mg  | >99%

AdipoGen Life Sciences

Substrate for determination of cytochrom P-450 dependent oxidases; about 50-100 times more sensitive than conventional substrate ethoxy-resorufin due to higher turn over rate.

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3-Cyanoumbelliferone 100 mg  | >98%

AdipoGen Life Sciences

Phenolic dyes with high pKas – such as 7-hydroxycoumarin (often called umbelliferone) and the more common 7-hydroxy-4-methylcoumarin – are not fully deprotonated and therefore not fully fluorescent unless the pH of the reaction mixture is raised to above pH ~10. Thus, substrates derived from these fluorophores are seldom used for continuous measurement of enzymatic activity […]

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3-Cyanoumbelliferone 1 g  | >98%

AdipoGen Life Sciences

Phenolic dyes with high pKas – such as 7-hydroxycoumarin (often called umbelliferone) and the more common 7-hydroxy-4-methylcoumarin – are not fully deprotonated and therefore not fully fluorescent unless the pH of the reaction mixture is raised to above pH ~10. Thus, substrates derived from these fluorophores are seldom used for continuous measurement of enzymatic activity […]

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3-Cyanoumbelliferone 5 g  | >98%

AdipoGen Life Sciences

Phenolic dyes with high pKas – such as 7-hydroxycoumarin (often called umbelliferone) and the more common 7-hydroxy-4-methylcoumarin – are not fully deprotonated and therefore not fully fluorescent unless the pH of the reaction mixture is raised to above pH ~10. Thus, substrates derived from these fluorophores are seldom used for continuous measurement of enzymatic activity […]

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3-Deoxyaphidicolin 250 µg  | >98%

AdipoGen Life Sciences

Inhibitor of eukaryotic DNA synthesis. Mycotoxin. Phytotoxic and cytotoxic agent. Specific inhibitor of DNA polymerase alpha.

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3-Deoxyaphidicolin 1 mg  | >98%

AdipoGen Life Sciences

Inhibitor of eukaryotic DNA synthesis. Mycotoxin. Phytotoxic and cytotoxic agent. Specific inhibitor of DNA polymerase alpha.

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3-Hydroxy-butanoyl-DL-homoserine lactone 5 mg  | >98%

AdipoGen Life Sciences

3-Hydroxy-butanoyl-DL-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.

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