2′-(4-Methylumbelliferyl)-alpha-D-N-acetylneuraminic acid sodium salt hydrate

Fluorogenic substrate used to measure sensitively enzymatic neuraminidase activity in fluorometric assays in mammalian and viral sources. Neuraminidase is catalyzed by the hydrolysation to form N-acetylneuraminic acid and the blue fluorescent soluble compound 4-Methylumbelliferone, which can be detected fluorometrically. Spectral data: lambdaex 315 nm| lambdaem 374 nm (pH.7.0) or lambdaex 365 nm| lambdaem 445 nm (after cleavage by neuraminidase). Used for fluorescent staining of sialidases in PAGE.

Catalog Number CDX-M0096-M001
Alternative Name(s) 4-MUNANA; 4-Methylumbelliferyl-N-acetyl-alpha-D-neuraminic acid sodium salt hydrate; Neu5Ac-alpha-4MU; 4MU-NeuNAc
Research Area Biochemicals, Immunology
Molecular Formula C21H24NNaO11 . xH2O
CAS# 76204-02-9 (anhydrous)
Purity >95%
Inchi InChI=1S/C21H25NO11.Na.H2O/c1-9-5-16(27)31-15-6-11(3-4-12(9)15)32-21(20(29)30)7-13(25)17(22-10(2)24)19(33-21)18(28)14(26)8-23;;/h3-6,13-14,17-19,23,25-26,28H,7-8H2,1-2H3,(H,22,24)(H,29,30);;1H2/q;+1;/p-1/t13-,14+,17+,18+,19+,21?;;/m0./s1
Inchi Key NSQMRVBWXQQIKF-HCNBQXOJSA-M
SMILES O.CC(=O)N[C@@H]1[C@H](O)C[C@@](OC2=CC3=C(C=C2)C(C)=CC(=O)O3)(OC1[C@H](O)[C@H](O)CO)C(=O)O[Na]
Size 1 mg
Supplier Page http://www.adipogen.com/cdx-m0096/2-4-methylumbelliferyl-alpha-d-n-acetylneuraminic-acid-sodium-salt-hydrate.html