A sulfanilamide that is used as an antibacterial agent. It can be used to treat bronchitis, prostatitis and urinary tract infections.Sulfonamides act as competitive inhibitors of the enzyme dihydropteroate synthetase (DHPS), an enzyme involved in folate synthesis in bacteria.

Benzoylecgonine is the compound tested for in most substantive cocaine urinalyses. It can be found in the urine for considerably longer than the cocaine itself which is generally cleared out within 5 days. It is formed in the liver by the metabolism of cocaine, catalysed by carboxylesterases, and subsequently excreted in the urine.

Biotin, also known as vitamin H or coenzyme R, is a water-soluble B-vitamin (vitamin B7). It is composed of a ureido (tetrahydroimidizalone) ring fused with a tetrahydrothiophene ring. A valeric acid substituent is attached to one of the carbon atoms of the tetrahydrothiophene ring. Biotin is a coenzyme for carboxylase enzymes, involved in the synthesis […]

Sulfadoxine is an ultra-long-lasting sulfonamide often used in combination with pyrimethamine to treat or prevent malaria. It is also used, usually in combination with other drugs, to treat or prevent various infections in livestock. Sulfadoxine competitively inhibits dihydropteroate synthase, interfering with folate synthesis.

Sulfadimethoxine is a controversial molecule used to treat some diseases occurring in pet animals.

Sulphadiazine is a competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle.

Folic acid and Folate (the anion form) are forms of a water-soluble B vitamin. These occur naturally in food and can also be taken as supplements. The biologically active form of folic acid is tetrahydrofolic acid (THFA), which is derived by the 2-step reduction of folate involving dihydrofolate reductase. THFA plays a key role in […]

Estriolis a hydroxylated metabolite of ESTRADIOL or ESTRONE that has a hydroxylgroup at C3-beta, 16-alpha, and 17-beta position. Estriol is the mainestrogen in the blood and urine of pregnant females. During pregnancy, largeamount of estriol is produced by the placenta. Serum estriol determinationsreflect the status of the fetus and are used to evaluate fetal distress […]