Selective N- and P/Q-type Ca2+-channel agonist. These Ca2+-channels regulate transmitter release in synapses. Potential lead compound for a variety of disorders that result in neuromuscular weakness.
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Potent antiprion agent. Higher activity than 6-Aminophenanthridine (Prod. No. MC-C0029). Ribosome-borne protein folding activity (RPFA) inhibitor. Binds to the ribosomal RNA and inhibits specifically the protein folding activity of the ribosome. Inhibitor of protein aggregation.
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N-methylated inactive control analog of 6-bromoindirubin-3′-oxime (6BIO) (Prod. No. MR-C0019). Displays minimal activity against CDK1/Cyclin B, GSK-3 alpha/beta and CDK5/p25. Aryl hydrocarbon receptor (AhR) agonist; causes redistribution of AhR to the nucleus.
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Potent and selective inhibitor of cyclin dependent kinases CDK1, CDK2, CDK5 and CDK9. Apoptosis inducer. Inhibits the proliferation of various cancer cell lines. Casein kinase 1 (CK1delta/epsilon) inhibitor. Potential anti-inflammatory compound. Potential antidiabetic compound.
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Potent and selective inhibitor of cyclin dependent kinases CDK1, CDK2, CDK5 and CDK9. Apoptosis inducer. Inhibits the proliferation of various cancer cell lines. Casein kinase 1 (CK1delta/epsilon) inhibitor. Potential anti-inflammatory compound. Potential antidiabetic compound.
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Potent and selective inhibitor of cyclin dependent kinases CDK1, CDK2, CDK5 and CDK9. Apoptosis inducer. Inhibits the proliferation of various cancer cell lines. Casein kinase 1 (CK1delta/epsilon) and DYRK1A inhibitor. Potential anti-inflammatory compound. Potential antidiabetic compound.
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Potent and selective inhibitor of cyclin dependent kinases CDK1, CDK2, CDK5 and CDK9. Apoptosis inducer. Inhibits the proliferation of various cancer cell lines. Casein kinase 1 (CK1delta/epsilon) and DYRK1A inhibitor. Potential anti-inflammatory compound. Potential antidiabetic compound.
More Information Supplier Page Potent and selective inhibitor of cyclin dependent kinases CDK1, CDK2, CDK5 and CDK9. Apoptosis inducer. Inhibits the proliferation of various cancer cell lines. Casein kinase 1 (CK1delta/epsilon) and DYRK1A inhibitor. Potential anti-inflammatory compound. Potential antidiabetic compound.
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Potent cyclin-dependent kinase (CDK) 1, 2, 5, and 9 inhibitor. Apoptosis inducer. Inhibits the proliferation of various cancer cell lines. Inhibits cysts formation in culture. Casein kinase 1 (CK1delta/epsilon) and Dyrk1A inhibitor. Down regulates expression of Mcl-1 and MYCN. Neuroprotective in experimental traumatic brain injury. Potential anti-inflammatory compound. Potential antidiabetic compound.
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Potent cyclin-dependent kinase (CDK) 1, 2, 5, and 9 inhibitor. Apoptosis inducer. Inhibits the proliferation of various cancer cell lines. Inhibits cysts formation in culture. Casein kinase 1 (CK1delta/epsilon) and Dyrk1A inhibitor. Down regulates expression of Mcl-1 and MYCN. Neuroprotective in experimental traumatic brain injury. Potential anti-inflammatory compound. Potential antidiabetic compound.
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