(S)-CR8

Potent cyclin-dependent kinase (CDK) 1, 2, 5, and 9 inhibitor. Apoptosis inducer. Inhibits the proliferation of various cancer cell lines. Inhibits cysts formation in culture. Casein kinase 1 (CK1delta/epsilon) and Dyrk1A inhibitor. Down regulates expression of Mcl-1 and MYCN. Neuroprotective in experimental traumatic brain injury. Potential anti-inflammatory compound. Potential antidiabetic compound.

Price Not Available 50 mg (S)-CR8 Supplier Page
Catalog Number AG-MR-C0004-M050
Alternative Name(s) 2-(S)-(1-Ethyl-2-hydroxyethylamino)-6-(4-(2-pyridyl)benzyl)-9-isopropylpurine
Research Area Apoptosis, Biochemicals, Cancer, Cell Death, Inflammation, Neurobiology
Molecular Formula C24H29N7O
CAS# 1084893-56-0
Purity >99%
Inchi InChI=1S/C24H29N7O/c1-4-19(14-32)28-24-29-22(21-23(30-24)31(15-27-21)16(2)3)26-13-17-8-10-18(11-9-17)20-7-5-6-12-25-20/h5-12,15-16,19,32H,4,13-14H2,1-3H3,(H2,26,28,29,30)/t19-/m0/s1
Inchi Key HOCBJBNQIQQQGT-IBGZPJMESA-N
SMILES CC[C@@H](CO)NC1=NC2=C(N=CN2C(C)C)C(NCC2=CC=C(C=C2)C2=NC=CC=C2)=N1
Size 50 mg
Supplier Page http://www.adipogen.com/mr-c0004/-s-cr8.html