AdipoGen Life Sciences
Fumitremorgin-type alkaloid. Tremorgenic neurotoxic mycotoxin. Selective blocker of KCa1.1 (high-conductance Ca2+-activated K+; BK; maxi-K) channels. Decreases GABA levels in CNS. Increases spontaneous glutamate and aspartate release. At toxic doses, increases the number and decreases the affinity of DHP receptors in rat cortex. Cell cycle inhibitor at the M phase. Inhibits calmodulin and PKC activity. Has […]
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AdipoGen Life Sciences
Antibiotic. Antibacterial and antiprotozoal (trypanocidal). Toxic to human A549 lung cells. Necrosis inducer. Toxic to human bronchial epithelial cells. Stimulating the growth of corn seedling roots. Inhibits IL-6 secretion, collagen IV and fibronectin production
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AdipoGen Life Sciences
Cell permeable, potent and selective cyclin-dependent kinase CDK-1 (CDC2), -2 and -5 inhibitor. Apoptosis inducer. Antitumor agent. Inhibits cell cycle progression at the G1/S and G2/M transitions. Shown to prevent the phosphorylation of retinoblastoma protein and H1 histone. Important probe for understanding the cellular roles of CDKs. Inhibitor of alpha-glucosidases. Maturation inhibitor of sheep oocytes.
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AdipoGen Life Sciences
Cell permeable, potent and selective cyclin-dependent kinase CDK-1 (CDC2), -2 and -5 inhibitor. Apoptosis inducer. Antitumor agent. Inhibits cell cycle progression at the G1/S and G2/M transitions. Shown to prevent the phosphorylation of retinoblastoma protein and H1 histone. Important probe for understanding the cellular roles of CDKs. Inhibitor of alpha-glucosidases. Maturation inhibitor of sheep oocytes.
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AdipoGen Life Sciences
20-Membered macrolide glycoside. Antibiotic and antifungal agent. Shows antitrypanosomal and antimalarial activity. Potent inhibitor of mitochondrial and bacterial ATP synthase. Inhibitor of F0F1-ATPase. Na+-translocating ATP synthases inhibitor.
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AdipoGen Life Sciences
Mycotoxin Antibacterial against Gram-positive bacteria. Shows antimalarial and antitubercular activity. Anticancer compound. Cytotoxic against several cancer cell lines (pro-apoptotic activity). Active against plant pathogene fungi (e.g. P. oryza, Phyt. infestans). Activator of murine T lymphocytes, NK cells and macrophages.
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AdipoGen Life Sciences
Derivative of Aphidicolin (BVT-0307) http://www.adipogen.com/bvt-0307/-aphidicolin.html . Mycotoxin. So far no comparison to aphidicolin’s biological activity (DNA polymerase alpha antiviral and antitumor activity) has been performed.
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AdipoGen Life Sciences
Derivative of Aphidicolin (BVT-0307) http://www.adipogen.com/bvt-0307/-aphidicolin.html . Mycotoxin. So far no comparison to aphidicolin’s biological activity (DNA polymerase alpha antiviral and antitumor activity) has been performed.
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AdipoGen Life Sciences
Inhibitor of eukaryotic DNA synthesis. Mycotoxin. Phytotoxic and cytotoxic agent. Specific inhibitor of DNA polymerase alpha.
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AdipoGen Life Sciences
Inhibitor of eukaryotic DNA synthesis. Mycotoxin. Phytotoxic and cytotoxic agent. Specific inhibitor of DNA polymerase alpha.
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