Peimine can inhibit the production of inflammatory cytokines induced by LPS and block MAPK and NF-κB signaling pathways. It is purified from the bulbus of fritillaria thunbergii.
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Peimine can inhibit the production of inflammatory cytokines induced by LPS and block MAPK and NF-κB signaling pathways. It is purified from the bulbus of fritillaria thunbergii.
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Silibinin is an antioxidant which shows inhibition of p-glycoprotein-mediated cellular efflux and obvious stability of liver cell membrane. Silibinin can be extracted from the herb of Silybum marianum (L.) Gaertn.
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Silibinin is an antioxidant which shows inhibition of p-glycoprotein-mediated cellular efflux and obvious stability of liver cell membrane. Silibinin can be extracted from the herb of Silybum marianum (L.) Gaertn.
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Hydroxyzine 2HCl is an antagonist of histamine H1-receptor that inhibits the binding of [3H]pyrilamine and [3H]desloratadine to histamine H1 receptor with IC50s of 10 nM and 19 nM.
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Diflunisal is a difluorophenyl derivate of salicylic acid and a nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic and anti-inflammatory properties. The mechanism of action of diflunisal is as a cyclooxygenase Inhibitor.
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Capecitabine is a tumor-selective fluoropyrimidine carbamate, which achieves higher intratumoral 5-FU level with lower toxicity than 5-FU, and used as an anti-cancer prodrug.
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Dexmedetomidine is a selectively activator of presynaptic alpha-2 adrenoceptors located in the brain. This leads to inhibition of postsynaptic activation of adrenoceptors through inhibiting the release of norepinephrine from synaptic vesicles, thereby leading to analgesia, sedation and anxiolysis.
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