This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of EZH2-derived peptide of YMCSFLFNL sequence covering 666-674 and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of LY6K-derived peptide of RYCNLEGPPI sequence covering 177-186 and A*24:02 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

CX-5461 is a first-in-class non-genotoxic small molecule targeted inhibitor of RNA polymerase I (Pol I) that activates the p53 pathway without causing DNA damage. CX-5461 selectively inhibits rRNA synthesis by Pol I in the nucleolus, but does not inhibit mRNA synthesis by RNA Polymerase II (Pol II) and does not inhibit DNA replication or protein […]

Remdesivir (RDV, GS-5734) is a broad-spectrum antiviral nucleotide prodrug with potent in vitro antiviral activity against a diverse panel of RNA viruses such as Ebola virus (EBOV), Marburg, MERS-CoV, SARS-CoV, respiratory syncytial virus, Nipah virus, Hendra virus, and possibly SARS-CoV-2 (the virus causing Covid-19 pandemic). Remdesivir is an adenosine analogue, which incorporates into nascent viral […]

ADCs cytotoxin, alpha-Amanitin is a potent inhibitor of DNA-dependent RNA polymerase II.

ADCs cytotoxin, 10-Deacetyl-7-xylosyl paclitaxel is a Paclitaxel derivative with ADCs cytotoxin,improved pharmacological features and higher water solubility.