(R)-FSL-1

R-FSL-1 (R-Pam2CGDPKHPKSF) is a synthetic lipoprotein that represents the N-terminal part of the 44kDa lipoprotein LP44 of Mycoplasma salivarium. The naturally occurring R-stereoisomer is biologically more active than the S-stereoisomer. Stimulator of TLR2/TLR6. Inducer of TNF-alpha production in macrophages. Upregulates proinflammatory cytokines. Activator of the proinflammatory transcription factor NF-kappaB.

Price Not Available 100 µg (R)-FSL-1 Supplier Page
Catalog Number AG-CP3-0010-C100
Alternative Name(s) Fibroblast-stimulating Lipopeptide; R-Pam2CGDPKHPKSF; (R)-Pam2Cys-Gly-Asp-Pro-Lys-His-Pro-Lys-Ser-Phe-OH
Research Area Biochemicals, Cancer, Inflammasomes, Inflammation
Molecular Formula C84H140N14O18S
Inchi InChI=1S/C84H140N14O18S/c1-3-5-7-9-11-13-15-17-19-21-23-25-30-44-74(103)115-56-62(116-75(104)45-31-26-24-22-20-18-16-14-12-10-8-6-4-2)57-117-58-63(87)76(105)89-54-72(100)91-67(52-73(101)102)83(112)98-49-37-43-71(98)81(110)92-64(40-32-34-46-85)77(106)94-66(51-61-53-88-59-90-61)82(111)97-48-36-42-70(97)80(109)93-65(41-33-35-47-86)78(107)96-69(55-99)79(108)95-68(84(113)114)50-60-38-28-27-29-39-60/h27-29,38-39,53,59,62-71,99H,3-26,30-37,40-52,54-58,85-87H2,1-2H3,(H,88,90)(H,89,105)(H,91,100)(H,92,110)(H,93,109)(H,94,106)(H,95,108)(H,96,107)(H,101,102)(H,113,114)/t62-,63+,64+,65+,66+,67+,68+,69+,70+,71+/m1/s1
Inchi Key VJJLLNHELGKSNA-QWIIDARVSA-N
SMILES [H][C@@](COC(=O)CCCCCCCCCCCCCCC)(CSC[C@]([H])(N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O)OC(=O)CCCCCCCCCCCCCCC
Size 100 µg
Supplier Page http://www.adipogen.com/ag-cp3-0010/-r-fsl-1.html