BLZ-945
Anticancer compound. Orally active, potent and selective colony stimulating factor 1 receptor (CSF-1R; c-Fms) inhibitor. More than 1000-fold selective against its closest receptor tyrosine kinase homologs c-KIT and platelet-derived growth factor receptor beta (PDGFRbeta). Selective against more than 200 additional kinases.
| Catalog Number | AG-CR1-3609-M001 |
| Alternative Name(s) | BLZ945 |
| Research Area | Apoptosis, Biochemicals, Cancer, Immunology |
| Molecular Formula | C20H22N4O3S |
| CAS# | 953769-46-5 |
| Purity | >95% |
| Inchi | InChI=1S/C20H22N4O3S/c1-21-19(26)16-10-13(8-9-22-16)27-12-6-7-15-18(11-12)28-20(24-15)23-14-4-2-3-5-17(14)25/h6-11,14,17,25H,2-5H2,1H3,(H,21,26)(H,23,24)/t14-,17-/m1/s1 |
| Inchi Key | ADZBMFGQQWPHMJ-RHSMWYFYSA-N |
| SMILES | CNC(=O)C1=CC(OC2=CC=C3N=C(N[C@@H]4CCCC[C@H]4O)SC3=C2)=CC=N1 |
| Size | 1 mg |
| Supplier Page | http://www.adipogen.com/ag-cr1-3609/blz-945.html |