Rebeccamycin
ADCs Toxins, An antibiotic composed of a halogenated indolocarbazole chromophore linked via N-glycosidic bond to a glucose derivative. It intercalates into the DNA and is an inhibitor of topoisomerase I. L1210: IC50 = 100 nM (mouse); K562: IC50 = 200 nM (human); A549: IC50 = 300 nM (human); B16 melanoma cells: IC50 = 480 nM (mouse); P388 leukemia cells: IC50 = 500 nM
Trivial name | Rebeccamycin |
Catalog Number | ADC-P-134 |
Alternative Name(s) | Rebeccamycin |
Research Area | ADC research |
CAS# | 93908-02-2 |
Purity | >95% |
Size | 1 mg |
Supplier Page | https://www.creative-biolabs.com/adc/classify-adc-toxins-6.htm |
Additional Information | Not fully tested. For research use only. Not for human use. We do not sell to patients. |