Rebeccamycin
Antibiotic. Weak topoisomerase I (Topo I) inhibitor. Structurally similar to staurosporine. Does not show any inhibitory activity against protein kinases. Shows significant antitumor properties in vitro (IC50 = 480 nM against mouse B16 melanoma cells and IC50 = 500 nM against P388 leukemia cells).
| Catalog Number | BVT-0139-C250 |
| Alternative Name(s) | NSC 359079; BRN 4732638 |
| Research Area | Antibiotic, Cancer, Immunology, Natural Products |
| Molecular Formula | C27H21Cl2N3O7 |
| CAS# | 93908-02-2 |
| Purity | >98% |
| Inchi | InChI=1S/C27H21Cl2N3O7/c1-38-24-13(8-33)39-27(23(35)22(24)34)32-20-10(5-3-7-12(20)29)15-17-16(25(36)31-26(17)37)14-9-4-2-6-11(28)18(9)30-19(14)21(15)32/h2-7,13,22-24,27,30,33-35H,8H2,1H3,(H,31,36,37)/t13-,22-,23-,24-,27-/m0/s1 |
| Inchi Key | QEHOIJJIZXRMAN-UMHCKEELSA-N |
| SMILES | COC1C(O)C(O)C(OC1CO)N1C2=C3NC4=C(C=CC=C4Cl)C3=C3C(=O)NC(=O)C3=C2C2=C1C(Cl)=CC=C2 |
| Size | 250 µg |
| Supplier Page | http://www.adipogen.com/bvt-0139/rebeccamycin.html |