6-(Dimethylamino)purine
A puromycin analog that acts as a protein kinase inhibitor. Selectively induces premature mitosis in mammalian cells. Inhibits TNF-alpha upregulation of ICAM-1, lipolysis, and the activation of JNK/SAPK. Inhibits p34cdc2/cyclin B (IC50 = 300 µM). Induces apoptosis in S-phase-arrested HeLa cells (~5 mM).
| Catalog Number | CDX-D0318-G001 |
| Research Area | Biochemicals, Cancer |
| Molecular Formula | C7H9N5 |
| CAS# | 938-55-6 |
| Purity | >97% |
| Inchi | InChI=1S/C7H9N5/c1-12(2)7-5-6(9-3-8-5)10-4-11-7/h3-4H,1-2H3,(H,8,9,10,11) |
| Inchi Key | BVIAOQMSVZHOJM-UHFFFAOYSA-N |
| SMILES | CN(C)C1=C2NC=NC2=NC=N1 |
| Size | 1 g |
| Supplier Page | http://www.adipogen.com/cdx-d0318/6-dimethylamino-purine.html |