PLX4720
Potent and selective cell permeable B-Raf (V600E) and c-Raf-1 (Y340D/Y341D) inhibitor. Antitumor compound. ERK phosphorylation is potently inhibited exclusive in B-Raf(V600E)-bearing tumor cell lines.
| Catalog Number | AG-CR1-3577-M005 |
| Alternative Name(s) | N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide |
| Research Area | Apoptosis, Biochemicals, Cancer, Cell Death |
| Molecular Formula | C17H14ClF2N3O3S |
| CAS# | 918505-84-7 |
| Purity | >99% |
| Inchi | InChI=1S/C17H14ClF2N3O3S/c1-2-5-27(25,26)23-13-4-3-12(19)14(15(13)20)16(24)11-8-22-17-10(11)6-9(18)7-21-17/h3-4,6-8,23H,2,5H2,1H3,(H,21,22) |
| Inchi Key | YZDJQTHVDDOVHR-UHFFFAOYSA-N |
| SMILES | CCCS(=O)(=O)NC1=CC=C(F)C(C(=O)C2=CNC3=NC=C(Cl)C=C23)=C1F |
| Size | 5 mg |
| Supplier Page | http://www.adipogen.com/ag-cr1-3577/plx4720.html |