SAG . dihydrochloride (water soluble)
Cell permeable Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Induces Sonic hedgehog (Shh) pathway activation and counteracts cyclopamine inhibition of Smo. Acts as an activator of Smo at low concentrations and as an inhibitor of Smo at very high concentrations. Potent activator of VEGF expression in vitro.
| Catalog Number | AG-CR1-3585-M005 |
| Alternative Name(s) | 3-Chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[3-(4-pyridinyl)benzyl]-1-benzothiophene-2-carboxamide . 2HCl |
| Research Area | Biochemicals, Cancer, Immunology, Stem Cell Research |
| Molecular Formula | C28H28ClN3OS . 2HCl . 3H2O |
| CAS# | 912545-86-9 and 364590-63-6 (both free base) |
| Purity | >98% |
| Inchi | InChI=1S/C28H28ClN3OS.2ClH.H2O/c1-30-22-9-11-23(12-10-22)32(28(33)27-26(29)24-7-2-3-8-25(24)34-27)18-19-5-4-6-21(17-19)20-13-15-31-16-14-20;;;/h2-8,13-17,22-23,30H,9-12,18H2,1H3;2*1H;1H2/t22-,23-;;; |
| Inchi Key | IYXUQUYRWPGIQL-KOONDFAVSA-N |
| SMILES | O.CNC1CCC(CC1)N(CC1=CC(=CC=C1)C1=CC=NC=C1)C(=O)C1=C(Cl)C2=CC=CC=C2S1 |
| Size | 5 mg |
| Supplier Page | http://www.adipogen.com/ag-cr1-3585/sag-dihydrochloride-water-soluble.html |