Bafilomycin B1

Macrolide antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Antitrypanosomal and antileishmanial compound. Phytotoxic. Influences the cell wall biosynthesis of Asp. niger.

Price Not Available 100 µg Bafilomycin B1 Supplier Page

Catalog Number	BVT-0004-C100
Alternative Name(s)	Setamycin; BRN4640118
Research Area	Antibiotic, Autophagy, Immunology, Natural Products
Molecular Formula	C44H65NO13
CAS#	88899-56-3
Purity	>97%
Inchi	InChI=1S/C44H65NO13/c1-23(2)41-28(7)35(56-37(49)18-17-36(48)45-38-31(46)15-16-32(38)47)22-44(53,58-41)30(9)40(51)29(8)42-33(54-10)14-12-13-24(3)19-26(5)39(50)27(6)20-25(4)21-34(55-11)43(52)57-42/h12-14,17-18,20-21,23,26-30,33,35,39-42,46,50-51,53H,15-16,19,22H2,1-11H3,(H,45,48)/b14-12-,18-17+,24-13+,25-20+,34-21-/t26-,27-,28+,29+,30?,33+,35-,39+,40-,41-,42-,44-/m1/s1
Inchi Key	KFUFLYSBMNNJTF-APLCIVFZSA-N
SMILES	[H][C@@]1(OC(=O)C(OC)=CC(C)=C[C@@H](C)[C@@H](O)[C@@H](C)CC(C)=CC=C/[C@@H]1OC)[C@@H](C)[C@@H](O)[C@H](C)[C@@]1(O)C[C@@H](OC(=O)C=CC(=O)NC2=C(O)CCC2=O)[C@H](C)C(O1)C(C)C
Size	100 µg
Supplier Page	http://www.adipogen.com/bvt-0004/bafilomycin-b1.html