Bafilomycin A1 (high purity)

Macrolide antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Distinguishes among different types of ATPases. Inhibitor of endosomal, lysosomal and vacuolar acidification. Prevents lysosomal Ca2+ uptake. Inhibitor of autophagic degradation by rising pH and thus inactivating the lysosomal acid hydrolases. Neuroprotective.

Price Not Available 100 µg Bafilomycin A1 (high purity) Supplier Page

Catalog Number	BVT-0252-C100
Alternative Name(s)	NSC381866
Research Area	Antibiotic, Autophagy, Immunology, Natural Products, Neurobiology
Molecular Formula	C35H58O9
CAS#	88899-55-2
Purity	>98%
Inchi	InChI=1S/C35H58O9/c1-19(2)32-24(7)27(36)18-35(40,44-32)26(9)31(38)25(8)33-28(41-10)14-12-13-20(3)15-22(5)30(37)23(6)16-21(4)17-29(42-11)34(39)43-33/h12-14,16-17,19,22-28,30-33,36-38,40H,15,18H2,1-11H3/b14-12-,20-13+,21-16+,29-17-/t22-,23-,24+,25+,26?,27-,28+,30+,31-,32-,33-,35-/m1/s1
Inchi Key	XDHNQDDQEHDUTM-AZJYDCQCSA-N
SMILES	[H][C@@]1(OC(=O)C=C(OC)C(C)=C[C@@H](C)[C@@H](O)[C@@H](C)CC(C)=CC=C[C@@H]1OC)[C@@H](C)[C@@H](O)[C@H](C)[C@@]1(O)C[C@@H](O)[C@H](C)[C@H](O1)C(C)C
Size	100 µg
Supplier Page	http://www.adipogen.com/bvt-0252/bafilomycin-a1.html