Butyrolactone I
Cell permeable, potent and selective cyclin-dependent kinase CDK-1 (CDC2), -2 and -5 inhibitor. Apoptosis inducer. Antitumor agent. Inhibits cell cycle progression at the G1/S and G2/M transitions. Shown to prevent the phosphorylation of retinoblastoma protein and H1 histone. Important probe for understanding the cellular roles of CDKs. Inhibitor of alpha-glucosidases. Maturation inhibitor of sheep oocytes.
Catalog Number | BVT-0448-M005 |
Research Area | Apoptosis, Biochemicals, Cancer, Cell Death, Natural Products |
Molecular Formula | C24H24O7 |
CAS# | 87414-49-1 |
Purity | >98% |
Inchi | InChI=1S/C24H24O7/c1-14(2)4-6-17-12-15(5-11-19(17)26)13-24(23(29)30-3)20(21(27)22(28)31-24)16-7-9-18(25)10-8-16/h4-5,7-12,25-27H,6,13H2,1-3H3 |
Inchi Key | NGOLMNWQNHWEKU-UHFFFAOYSA-N |
SMILES | COC(=O)[C@]1(CC2=CC=C(O)C(CC=C(C)C)=C2)OC(=O)C(O)=C1C1=CC=C(O)C=C1 |
Size | 5 mg |
Supplier Page | http://www.adipogen.com/bvt-0448/butyrolactone-i.html |