Cyclosporin H
Potent inhibitor of tumor promoting phorbol ester TPA/PMA (AG-CN2-0010) effects in vivo. Antifungal. Potent and effective inhibitor of formyl peptide receptor (FPR) and formyl peptide-induced superoxide formation. Shows no immunosuppresive activity like other cyclosporins.
| Catalog Number | AG-CN2-0447-M001 |
| Alternative Name(s) | D-MeVal11-Cyclosporine; CsH |
| Research Area | Antibiotic, Apoptosis, Cancer, Immunology, Inflammation, Natural Products, Stem Cell Research |
| Molecular Formula | C62H111N11O12 |
| CAS# | 83602-39-5 |
| Purity | >97% |
| Inchi | InChI=1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59(82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h25,27,34-47,49-52,75H,26,28-33H2,1-24H3,(H,63,77)(H,64,76)(H,65,79)(H,66,78)/b27-25-/t40-,41+,42-,43+,44+,45+,46+,47+,49+,50+,51+,52-/m1/s1 |
| Inchi Key | PMATZTZNYRCHOR-DAYHEYMASA-N |
| SMILES | [H][C@@]1([C@H](O)[C@H](C)CC=CC)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)C(CC)NC1=O)C(C)C |
| Size | 1 mg |
| Supplier Page | http://www.adipogen.com/ag-cn2-0447/cyclosporin-h.html |