10Z-Hymenialdisine

Insecticidal and cytotoxic. Potent NF-kappaB inhibitor. Inhibits various pro-inflammatory cytokines such as IL-1, IL-2, IL-6, IL-8, TNF-alpha and nitric oxide (NO) in a variety of cell lines. ATP-competitive kinase inhibitor. Inhibits DNA damage checkpoint at G2, cyclin-dependent kinases CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E, CDK4/cyclin D1, CDK5/p25, GSK-3beta and casein kinase 1 (CK1). Potent mitogen-activated protein kinase kinase-1 (MEK-1) inhibitor. MARK (microtubule affinity-regulating kinase) inhibitor.

Price Not Available 500 µg 10Z-Hymenialdisine Supplier Page
Catalog Number AG-CN2-0067-C500
Alternative Name(s) Hymenialdisine; 4-(2-Amino-4-oxo-2-imidazolidin-5-ylidene)-2-bromo-4,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8-one
Research Area Cancer, Inflammation, Natural Products
Molecular Formula C11H10BrN5O2
CAS# 82005-12-7
Purity >97%
Inchi InChI=1S/C11H10BrN5O2/c12-6-3-5-4(7-10(19)17-11(13)16-7)1-2-14-9(18)8(5)15-6/h3,15H,1-2H2,(H,14,18)(H3,13,16,17,19)/b7-4-
Inchi Key ATBAETXFFCOZOY-DAXSKMNVSA-N
SMILES NC1=NC(=O)C(N1)=C1/CCNC(=O)C2=C1C=C(Br)N2
Size 500 µg
Supplier Page http://www.adipogen.com/ag-cn2-0067/10z-hymenialdisine.html