Concanamycin B (high purity)

Antibiotic. Exhibits similar activity as concanamycin A (Prod. No. BVT-0237) and concanamycin C (Prod. No. BVT-0254). Specific vacuolar-type H+-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Suppresses bone resorption. Inhibits proliferation of mouse splenic lymphocytes. Antifungal and larvicidal.

Price Not Available 100 µg Concanamycin B (high purity) Supplier Page

Catalog Number	BVT-0253-C100
Alternative Name(s)	8-Deethyl-8-methylconcanamycin A
Research Area	Antibiotic, Autophagy, Bone Research, Cancer, Immunology, Natural Products
Molecular Formula	C45H73NO14
CAS#	81552-33-2
Purity	>98%
Inchi	InChI=1S/C45H73NO14/c1-13-15-33-27(6)36(57-37-21-32(47)42(31(10)56-37)59-44(46)52)22-45(53,60-33)30(9)40(50)29(8)41-34(54-11)17-14-16-23(2)18-25(4)38(48)28(7)39(49)26(5)19-24(3)20-35(55-12)43(51)58-41/h13-17,19-20,25-34,36-42,47-50,53H,18,21-22H2,1-12H3,(H2,46,52)/b15-13+,17-14+,23-16-,24-19+,35-20-/t25-,26-,27-,28+,29+,30+,31-,32-,33-,34?,36-,37+,38+,39-,40-,41+,42-,45-/m1/s1
Inchi Key	AQXXGIBOZQZSAT-UZYXLCJWSA-N
SMILES	[H][C@@]1(C[C@@H](O)[C@H](OC(N)=O)[C@@H](C)O1)O[C@@H]1C[C@@](O)(O[C@H](C=CC)[C@H]1C)[C@@H](C)[C@H](O)[C@H](C)[C@]1([H])OC(=O)C(OC)=CC(C)=C[C@@H](C)[C@@H](O)[C@@H](C)[C@@H](O)[C@H](C)CC(C)=CC=C[C@@H]1OC
Size	100 µg
Supplier Page	http://www.adipogen.com/bvt-0253/concanamycin-b.html