Hypothemycin

ADCs Toxins, Exhibits antifungal and cytotoxic activity against some tumor cell lines partly attributed to inhibition of Ras-inducible genes. Inhibits proliferation of mouse and human T cells and modulates production of cytokines during T cell activation. Facilitates the ubiquitinylation process of cyclin D1. Has been identified as a potent and selective inhibitor of threonine/tyrosine-specific kinase, MEK, and other protein kinases that contain a conserved cysteine residue in the ATP-binding site in both in vitro and in vivo studies. HCT-116: IC50=0,0026 uM; PSN1 : IC50=0,26 uM; T98G : IC50=2,6 uM; A549 : IC50=0,26 uM (preliminary laboratory results). Journal of Natural Products (2011), 74(5), 1126-1131.

Price Not Available 1 mg Hypothemycin Supplier Page
Trivial name Hypothemycin
Catalog Number ADC-P-100
Alternative Name(s) Hypothemycin
Research Area ADC research
CAS# 76958-67-3
Purity >95%
Size 1 mg
Supplier Page https://www.creative-biolabs.com/adc/classify-adc-toxins-6.htm
Additional Information Not fully tested. For research use only. Not for human use. We do not sell to patients.