Ingenol-3-angelate
Specific protein kinase C (PKC) activator. Selective activator of PKC isoforms, like PKCtheta in T cells. Antiproliferative and proapoptotic (necrotic). Immunostimulant. Chemotherapeutic. Anticancer compound. Efficacious agent against actinic kerastosis. Antileukemic.
| Catalog Number | AG-CN2-0012-M005 |
| Alternative Name(s) | PEP005; I3A |
| Research Area | Cancer, Immunology, Natural Products |
| Molecular Formula | C25H34O6 |
| CAS# | 75567-37-2 |
| Purity | >97% |
| Inchi | InChI=1S/C25H34O6/c1-7-12(2)22(29)31-21-13(3)10-24-14(4)8-17-18(23(17,5)6)16(20(24)28)9-15(11-26)19(27)25(21,24)30/h7,9-10,14,16-19,21,26-27,30H,8,11H2,1-6H3/b12-7-/t14-,16+,17?,18+,19-,21+,24+,25+/m1/s1 |
| Inchi Key | VDJHFHXMUKFKET-XCHJBCONSA-N |
| SMILES | [H][C@@]12C(C[C@@H](C)[C@]34C=C(C)[C@H](OC(=O)C(C)=C/C)[C@@]3(O)[C@H](O)C(CO)=C[C@]1([H])C4=O)C2(C)C |
| Size | 5 mg |
| Supplier Page | http://www.adipogen.com/ag-cn2-0012/ingenol-3-angelate.html |