Nargenicin A1
Antibiotic against Gram-positive bacteria, particularly Staphylococcus and Clostridia. More effective against multi-resistant strains (MRSA) than erythromycin and vancomycin. Inhibits cell proliferation and induces HL-60 cell differentiation in combination with 1,25-Dihydroxyvitamin-D3 and ATRA. Displays low cytotoxicity compared to erythromycin and spiramycin.
Catalog Number | BVT-0204-M001 |
Alternative Name(s) | CP-47,444; CS682 |
Research Area | Antibiotic, Cancer, Immunology, Natural Products |
Molecular Formula | C28H37NO8 |
CAS# | 70695-02-2 |
Purity | >98% |
Inchi | InChI=1S/C28H37NO8/c1-13-11-14(2)28-17(12-20(34-5)27(33)35-23(13)16(4)30)8-9-18-21(28)22(31)15(3)24(25(18)37-28)36-26(32)19-7-6-10-29-19/h6-11,13,15-18,20-25,29-31H,12H2,1-5H3/b14-11+/t13-,15-,16-,17-,18-,20+,21+,22-,23+,24-,25-,28+/m1/s1 |
Inchi Key | YEUSSARNQQYBKH-SIMZXIQRSA-N |
SMILES | [H][C@]12C=C[C@]3([H])C[C@H](OC)C(=O)O[C@]([H])([C@@H](C)O)[C@H](C)C=C(C)[C@]33O[C@H]1[C@H](OC(=O)C1=CC=CN1)[C@H](C)[C@@H](O)[C@]23[H] |
Size | 1 mg |
Supplier Page | http://www.adipogen.com/bvt-0204/nargenicin-a1.html |