Ganglioside GQ1b . tetrasodium salt (bovine brain)

Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GQ1b specifically promotes neural differentiation of human neuroblastoma cells. Anti-GQ1b antibodies are present in serum from Miller-Fisher syndrome patients.

Price Not Available 500 µg Ganglioside GQ1b . tetrasodium salt (bovine brain) Supplier Page

Catalog Number	AG-CN2-9007-C500
Alternative Name(s)	GQ1b . 4Na; Tetrasialoganglioside GQ1b . 4Na
Research Area	Cancer, Inflammation, Natural Products, Neurobiology, Neurodegenerative Disease
Molecular Formula	C106H178N6O55 . 4Na
CAS#	68652-37-9
Purity	>98%
Inchi	InChI=1S/C106H182N6O55.4Na/c1-8-10-12-14-16-18-20-22-23-25-27-29-31-33-35-37-70(133)112-56(57(126)36-34-32-30-28-26-24-21-19-17-15-13-11-9-2)50-152-96-83(141)82(140)86(68(48-119)155-96)157-98-85(143)94(167-106(102(150)151)41-61(130)74(110-54(6)124)92(165-106)81(139)67(47-118)161-104(100(146)147)39-59(128)72(108-52(4)122)90(163-104)77(135)63(132)43-114)87(69(49-120)156-98)158-95-75(111-55(7)125)88(78(136)64(44-115)153-95)159-97-84(142)93(79(137)65(45-116)154-97)166-105(101(148)149)40-60(129)73(109-53(5)123)91(164-105)80(138)66(46-117)160-103(99(144)145)38-58(127)71(107-51(3)121)89(162-103)76(134)62(131)42-113;;;;/h34,36,56-69,71-98,113-120,126-132,134-143H,8-33,35,37-50H2,1-7H3,(H,107,121)(H,108,122)(H,109,123)(H,110,124)(H,111,125)(H,112,133)(H,144,145)(H,146,147)(H,148,149)(H,150,151);;;;/q;4*+1/p-4/b36-34+;;;;/t56-,57+,58?,59?,60?,61?,62+,63+,64?,65?,66-,67-,68?,69?,71+,72+,73+,74+,75?,76-,77-,78-,79+,80-,81-,82?,83?,84?,85?,86+,87-,88?,89?,90?,91?,92?,93?,94?,95+,96+,97-,98-,103+,104+,105-,106-;;;;/m0../s1
Inchi Key	QISNAVHLOKDTLS-UTKQHEHRSA-J
SMILES	[Na+].[Na+].[Na+].[Na+].[H][C@@](O)(CO)[C@]([H])(O)C1O[C@@](CC(O)[C@H]1NC(C)=O)(O[C@@]([H])(CO)[C@]([H])(O)C1O[C@@](CC(O)[C@H]1NC(C)=O)(O[C@H]1[C@H](O)C(CO)O[C@@H](OC2[C@@H](O)[C@H](CO)O[C@H](O[C@H]3C(CO)O[C@@H](O[C@H]4C(O)C(O)[C@H](OC[C@]([H])(NC(=O)CCCCCCCCCCCCCCCCC)[C@]([H])(O)C=CCCCCCCCCCCCCC)O[C@H]4CO)C(O)[C@H]3O[C@@]3(CC(O)[C@@H](NC(C)=O)C(O3)[C@@]([H])(O)[C@]([H])(CO)O[C@@]3(CC(O)[C@@H](NC(C)=O)C(O3)[C@@]([H])(O)[C@]([H])(O)CO)C([O-])=O)C([O-])=O)C2NC(C)=O)C1O)C([O-])=O)C([O-])=O
Size	500 µg
Supplier Page	http://www.adipogen.com/ag-cn2-9007/ganglioside-gq1b-tetrasodium-salt.html