Thapsigargin (high purity)
Intracellular Ca2+ signaling probe. Specific and sensitive inhibitor of SERCA. Non-TPA/PMA tumor promoter. Histamine release inducer. Apoptosis inducer. Mitochondrial dysfunction inducer. NOS modulator. Angiogenesis inhibitor. Stimulator of arachidonic acid metabolism in macrophages. Autophagy inducer. TRAIL sensitizer.
Catalog Number | AG-CN2-0003-M010 |
Research Area | Cancer, Inflammation, Metabolism, Natural Products |
Molecular Formula | C34H50O12 |
CAS# | 67526-95-8 |
Purity | >98% |
Inchi | InChI=1S/C34H50O12/c1-9-12-13-14-15-17-24(37)43-28-26-25(20(5)27(28)44-30(38)19(4)11-3)29-34(41,33(8,40)31(39)45-29)22(42-23(36)16-10-2)18-32(26,7)46-21(6)35/h11,22,26-29,40-41H,9-10,12-18H2,1-8H3/b19-11-/t22-,26-,27-,28+,29?,32-,33-,34-/m1/s1 |
Inchi Key | IXFPJGBNCFXKPI-IVRBKYRWSA-N |
SMILES | [H][C@]12[C@H](OC(=O)CCCCCCC)[C@H](OC(=O)C(C)=C/C)C(C)=C1C1OC(=O)[C@@](C)(O)[C@@]1(O)[C@@H](C[C@@]2(C)OC(C)=O)OC(=O)CCC |
Size | 10 mg |
Supplier Page | http://www.adipogen.com/ag-cn2-0003/thapsigargin.html |