FK-866
Nampt/visfatin inhibitor. Inhibitor of NAD+ biosynthesis. Inhibits the enzyme/substrate complex and the free enzyme (Ki = 0.4 nM and Ki = 0.3 nM, respectively). Apoptosis inducer. Autophagy inducer. Causes premature senescence. Angiogenesis inhibitor.
| Catalog Number | AG-CR1-0011-M001 |
| Alternative Name(s) | K 22.175; FK866; APO866; WK175; N-[4-(1-Benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2E-propenamide |
| Research Area | Biochemicals, Cancer, Metabolism |
| Molecular Formula | C24H29N3O2 |
| CAS# | 658084-64-1 |
| Purity | >98% |
| Inchi | InChI=1S/C24H29N3O2/c28-23(12-11-21-8-6-15-25-19-21)26-16-5-4-7-20-13-17-27(18-14-20)24(29)22-9-2-1-3-10-22/h1-3,6,8-12,15,19-20H,4-5,7,13-14,16-18H2,(H,26,28)/b12-11+ |
| Inchi Key | KPBNHDGDUADAGP-VAWYXSNFSA-N |
| SMILES | O=C(NCCCCC1CCN(CC1)C(=O)C1=CC=CC=C1)C=CC1=CC=CN=C1 |
| Size | 1 mg |
| Supplier Page | http://www.adipogen.com/ag-cr1-0011/fk-866.html |