Cyclosporin D
Potent inhibitor of tumor promoting phorbol ester TPA/PMA (AG-CN2-0010) effects in vivo. Antifungal. Moderate immunosuppressant. Calcineurin inhibitor with lower activity than Cyclosporin A (AG-CN2-0079). Moderate inhibitor of formyl peptide-induced superoxide formation.
| Catalog Number | AG-CN2-0445-M001 |
| Alternative Name(s) | Val2-Cyclosporine; CsD |
| Research Area | Antibiotic, Apoptosis, Cancer, Immunology, Inflammation, Natural Products, Stem Cell Research |
| Molecular Formula | C63H113N11O12 |
| CAS# | 63775-96-2 |
| Purity | >97% |
| Inchi | InChI=1S/C63H113N11O12/c1-26-27-28-41(16)53(76)52-57(80)67-49(38(10)11)61(84)68(19)33-48(75)69(20)44(29-34(2)3)56(79)66-50(39(12)13)62(85)70(21)45(30-35(4)5)55(78)64-42(17)54(77)65-43(18)58(81)71(22)46(31-36(6)7)59(82)72(23)47(32-37(8)9)60(83)73(24)51(40(14)15)63(86)74(52)25/h26-27,34-47,49-53,76H,28-33H2,1-25H3,(H,64,78)(H,65,77)(H,66,79)(H,67,80)/b27-26-/t41-,42+,43-,44+,45+,46+,47+,49-,50+,51+,52+,53-/m1/s1 |
| Inchi Key | ZNVBEWJRWHNZMK-AHWIEGLVSA-N |
| SMILES | [H][C@@]1([C@H](O)[C@H](C)CC=CC)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)C(NC1=O)C(C)C)C(C)C |
| Size | 1 mg |
| Supplier Page | http://www.adipogen.com/ag-cn2-0445/cyclosporin-d.html |