(R)-3-Hydroxybutyric acid

Key metabolite of the ketolytic pathway generating acetyl-CoA. Stereoselective product of D-3-hydroxybutyrate dehydreogenase. Clinically and physiologically significant stereoisomer. Energy carrier from adipocytes to peripheral tissues during fasting or exercise. Endogenous inhibitor of histone deacetylases (HDACs) 1, 3 and 4. Ligand of free fatty acid receptor 3 (FFAR3; GPR41) and hydroxycarboxylic acid receptor 2 (HCAR2; GPR109B). NLRP3 inflammasome inhibitor. Prevents K+-efflux and reduces ASC oligomerization and speck formation.

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Catalog Number	AG-CR1-3616-M100
Alternative Name(s)	(R)-beta-Hydroxybutyric acid; D-(-)-3-Hydroxybutyric acid; D-(-)-BHB
Research Area	Biochemicals, Inflammasomes, Inflammation, Metabolism
Molecular Formula	C4H8O3
CAS#	625-72-9
Purity	>98%
Inchi	InChI=1S/C4H8O3/c1-3(5)2-4(6)7/h3,5H,2H2,1H3,(H,6,7)/t3-/m1/s1
Inchi Key	WHBMMWSBFZVSSR-GSVOUGTGSA-N
SMILES	C[C@@H](O)CC(O)=O
Size	100 mg
Supplier Page	http://www.adipogen.com/ag-cr1-3616/-r-3-hydroxybutyric-acid.html