Trichostatin A

Antibiotic. Antifungal. Antiprotozoal. Potent and reversible, cell permeable inhibitor of histone deacetylase (HDAC). Immunosuppressive. Anticancer compound. Antifibrogenic. Apoptosis inducer. Induces cell growth arrest at both G1 and G2/M phases. Enhances the efficacy of anticancer agents that target DNA. Inactivates mitotic spindle checkpoint. Smooth muscle cell proliferation inhibitor. Telomerase inhibitor. Downregulates DNA methyltransferase DNMT1 and affects DNA methylation. Anti-inflammatory. Inhibits osteoclastogenesis and bone resorption. Promotes either self-renewal or differentiation of embryonic stem cells.

Price Not Available 1 mg Trichostatin A Supplier Page
Catalog Number AG-CN2-0108-M001
Alternative Name(s) TSA; A300; R-(E,E)-7-(4-(dimethylamino)phenyl)-N-hydroxy- 4,6-dimethyl-7-oxo-2,4-heptadienamide
Research Area Antibiotic, Apoptosis, Bone Research, Cancer, Cell Death, Immunology, Inflammation, Natural Products, Stem Cell Research
Molecular Formula C17H22N2O3
CAS# 58880-19-6
Purity >95%
Inchi InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-11,13,22H,1-4H3,(H,18,20)/b10-5+,12-11+/t13-/m1/s1
Inchi Key RTKIYFITIVXBLE-QEQCGCAPSA-N
SMILES C[C@H](C=C(/C)C=CC(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C
Size 1 mg
Supplier Page http://www.adipogen.com/ag-cn2-0108/trichostatin-a.html