Wedelolactone

Cell permeable, selective and irreversible IKKalpha and beta kinase activity inhibitor. NF-kappaB inhibitor. Blocks phosphorylation and degradation of IkappaBalpha. Antihepatotoxic. 5-Lipoxygenase (5-LOX) inhibitor. Anti-inflammatory. HIV-1 integrase inhibitor. Anticancer and antiproliferative compound. Modulates androgen receptor (AR) activation. Apoptosis inducer via downregulation of PKCepsilon. DNA topoisomerase IIalpha inhibitor. G protein-coupled receptor-35 (GPR35) agonist. Inhibits adipogenic differentiation of mesenchymal stem cells (hAMSCs) through ERK pathway. STAT1 protein dephosphorylation inhibitor. Antifibrotic.

Price Not Available 5 mg Wedelolactone Supplier Page
Catalog Number AG-CN2-0424-M005
Alternative Name(s) 7-Methoxy-5,11,12-trihydroxy-coumestan; WDL
Research Area Apoptosis, Biochemicals, Cancer, Cell Death, Inflammation, Natural Products
Molecular Formula C16H10O7
CAS# 524-12-9
Purity >98%
Inchi InChI=1S/C16H10O7/c1-21-6-2-10(19)14-12(3-6)23-16(20)13-7-4-8(17)9(18)5-11(7)22-15(13)14/h2-5,17-19H,1H3
Inchi Key XQDCKJKKMFWXGB-UHFFFAOYSA-N
SMILES COC1=CC(O)=C2C3=C(C4=C(O3)C=C(O)C(O)=C4)C(=O)OC2=C1
Size 5 mg
Supplier Page http://www.adipogen.com/ag-cn2-0424/wedelolactone.html