Emodin
p56lck protein kinase inhibitor. Competitive casein kinase II (CK2) inhibitor. Anticancer agent with apoptosis inducing with antiangiogenic activity. Antioxidant, vasorelaxant and neuroprotective agent. NF-kappaB activation inhibitor. Inflammasome inhibitor. Potent selective 11beta-HSD1 inhibitor. Improves insulin sensitivity and lipid metabolism. Estrogen receptor ERalpha and ERbeta inhibitor. Inhibits androgen receptor (AR) nuclear translocation and induces AR degradation. VEGFR2, FGFR-1, EGFR, PDGFR-beta and Kit inhibitor. JAK2 inhibitor. Anti-diabetic agent. AMPK activator and PPARgamma agonist. Adipogenesis inhibitor. P2X7 receptor antagonist. Wnt signaling & PI3K/Akt/GSK-3beta pathway modulator.
Catalog Number | AG-CN2-0457-M050 |
Alternative Name(s) | Emodol; Frangulic acid; Archin; NSC 622947; NSC 408120; 1,3,8-Trihydroxy-6-methylanthraquinone; Schuttgelb |
Research Area | Antibiotic, Apoptosis, Cancer, Immunology, Inflammasomes, Inflammation, Metabolism, Natural Products |
Molecular Formula | C15H10O5 |
CAS# | 518-82-1 |
Purity | >98% |
Inchi | InChI=1S/C15H10O5/c1-6-2-8-12(10(17)3-6)15(20)13-9(14(8)19)4-7(16)5-11(13)18/h2-5,16-18H,1H3 |
Inchi Key | RHMXXJGYXNZAPX-UHFFFAOYSA-N |
SMILES | CC1=CC2=C(C(O)=C1)C(=O)C1=C(C=C(O)C=C1O)C2=O |
Size | 50 mg |
Supplier Page | http://www.adipogen.com/ag-cn2-0457/emodin.html |