17-DMAG

Less toxic, more potent synthetic derivative of geldanamycin (Prod. No. BVT-0196). Angiogenesis inhibitor. Heat shock protein 90 (HSP90) inhibitor. Apoptosis inducer. Shows higher antitumor activity than 17-AAG (Prod. No. BVT-0244).

Price Not Available 1 mg 17-DMAG Supplier Page
Catalog Number BVT-0255-M001
Alternative Name(s) NSC 707545; 17-[2-(Dimethylamino)ethyl]amino-17-desmethoxygeldanamycin
Research Area Apoptosis, Cancer, Cell Death, Natural Products
Molecular Formula C32H48N4O8
CAS# 467214-20-6
Purity >98%
Inchi InChI=1S/C32H48N4O8/c1-18-14-22-27(34-12-13-36(5)6)24(37)17-23(29(22)39)35-31(40)19(2)10-9-11-25(42-7)30(44-32(33)41)21(4)16-20(3)28(38)26(15-18)43-8/h9-11,16-18,20,25-26,28,30,34,38H,12-15H2,1-8H3,(H2,33,41)(H,35,40)/b11-9-,19-10+,21-16+/t18-,20+,25+,26+,28-,30+/m1/s1
Inchi Key KUFRQPKVAWMTJO-LMZWQJSESA-N
SMILES [H][C@@]1(C[C@@H](O)[C@H](O)[C@@H](C)O1)O[C@@H]1C[C@@](O)(O[C@H](C=CC)[C@H]1C)[C@@H](C)[C@H](O)[C@H](C)[C@@]1([H])OC(=O)C(OC)=CC(C)=C[C@@H](C)[C@@H](O)[C@H](CC)[C@H](O)[C@H](C)CC(C)=CC=C[C@@H]1OC
Size 1 mg
Supplier Page http://www.adipogen.com/bvt-0255/17-dmag.html