Gitoxin
Cardiac glycoside. Natural metabolite of digitoxin. Starting material for the synthesis of gitoxin derivatives with activity as cardiac glycosides. Uncompetitive inhibitor of the Na+/K+ ATPase activity. Inhibits growth of selected human cancer cells.
Catalog Number | AG-CN2-0485-M025 |
Alternative Name(s) | Anhydrogitalin; Bigitalin; Pseudodigitoxin; NSC 95099; BRN0077015 |
Research Area | Biochemicals, Cancer, Immunology, Natural Products |
Molecular Formula | C41H64O14 |
CAS# | 4562-36-1 |
Purity | >95% |
Inchi | InChI=1S/C41H64O14/c1-19-36(47)27(42)14-33(50-19)54-38-21(3)52-34(16-29(38)44)55-37-20(2)51-32(15-28(37)43)53-24-8-10-39(4)23(13-24)6-7-26-25(39)9-11-40(5)35(22-12-31(46)49-18-22)30(45)17-41(26,40)48/h12,19-21,23-30,32-38,42-45,47-48H,6-11,13-18H2,1-5H3/t19-,20-,21-,23-,24+,25+,26-,27+,28+,29+,30+,32+,33+,34+,35+,36-,37-,38-,39+,40-,41+/m1/s1 |
Inchi Key | LKRDZKPBAOKJBT-CNPIRKNPSA-N |
SMILES | O[C@@H]1[C@H](O)[C@@H](C)O[C@@H](O[C@H]([C@@H](C)O[C@@H](O[C@H]([C@@H](C)O[C@@H](O[C@H](C[C@@]2([H])CC[C@]3([H])[C@]4([H])CC[C@@]5([C@H]([C@@H](O)C[C@]35O)C(CO6)=CC6=O)C)CC[C@@]24C)C7)[C@H]7O)C8)[C@H]8O)C1 |
Size | 25 mg |
Supplier Page | http://www.adipogen.com/ag-cn2-0485/gitoxin.html |