NU6102
Potent CDK1/cyclin B (IC50 = 9.5 nM) and CDK2/cyclin A3 (IC50 = 5.4 nM) inhibitor. 1’000-fold more potent than NU2058. Selective for CDK1 and CDK2 compared to CDK4/D1 (IC50 = 1.6 µM), DYRK1A (IC50 = 0.9 µM), PDK1 (IC50 = 0.8 µM) and ROCK-II (IC50 = 0.6 µM). Inhibits cell growth.
| Catalog Number | AG-CR1-0020-M001 |
| Alternative Name(s) | O6-Cyclohexylmethyl-2-(4-sulfamoylanilino)purine |
| Research Area | Biochemicals, Cancer |
| Molecular Formula | C18H22N6O3S |
| CAS# | 444722-95-6 |
| Purity | >98% |
| Inchi | InChI=1S/C18H22N6O3S/c19-28(25,26)14-8-6-13(7-9-14)22-18-23-16-15(20-11-21-16)17(24-18)27-10-12-4-2-1-3-5-12/h6-9,11-12H,1-5,10H2,(H2,19,25,26)(H2,20,21,22,23,24) |
| Inchi Key | OWXORKPNCHJYOF-UHFFFAOYSA-N |
| SMILES | NS(=O)(=O)C1=CC=C(NC2=NC3=C(N=CN3)C(OCC3CCCCC3)=N2)C=C1 |
| Size | 1 mg |
| Supplier Page | http://www.adipogen.com/ag-cr1-0020/nu6102.html |